This issue of Clinics in Perinatology, guest edited by Drs. George Macones and Anthony Odibo, addresses Fetal Monitoring and Assessment. Drs. Macones and Odibo have assembled a panel of experts to pen reviews on topics including indications for fetal growth monitoring and controversies with diagnosis of fetal growth restriction, the role of serum markers and uterine artery Doppler in identifying at-risk pregnancies, the role of amniotic fluid assessment in evaluating fetal well-being, the uses and limitations of the biophysical profile, the umbilical artery Doppler in assessment of fetal growth restriction, the MCA Doppler and its role in evaluation of fetal anemia and fetal growth restriction, Venous Doppler evaluation of the growth restricted fetus, aortic isthmus and cardiac monitoring of the growth restricted fetus, intrapartum fetal monitoring, computerized assessment of fetal heart rate monitoring, STAN as an adjunct to EFM, and signal ambiguity and intrapartum fetal monitoring.

This issue of Clinics in Laboratory Medicine, Guest Edited by Anthony Odibo and David Krantz, will feature article topics such as: Screening for Chromosomal abnormalities; Cystic fibrosis screening; The role of second-trimester screening, in the post-first trimester screening era; Modifying risk for Aneuploidy with second-trimester ultrasound after a positive serum screen; Cost-effectiveness of Down syndrome screening paradigms; Biochemical and biophysical screening for the risk of Preterm delivery; Pre-implantation genetic diagnosis; Prenatal testing for infectious disease, Thrombophilias, Preeclampsia, Neural Tube Defects; Management of Multiple Pregnancy; Genetic Counseling Issues in Down syndrome Screening; First Trimester Ultrasound Markers; Quality Control of Nuchal Translucency; Clinical Implications of First Trimester Screening; Adverse Pregnancy Outcomes after Positive Screening; First Trimester Combined Screening: Instant Risks Approach.

This issue of Clinics in Laboratory Medicine, edited by Drs. Anthony Odibo and David A. Krantz, covers issues surrounding Prenatal Screening and Diagnosis. Topics examined in this issue include, but are not limited to: Strategies for Implementing cfDNA Testing; Genetic Counselling for Patients Considering Screening and Diagnosis of Chromosomal Abnormalities; Microdeletions/Duplications; Sex Chromosome Abnormalities; First-, Second- and Third-Trimester Screening for Preeclampsia and Intrauterine Growth Restriction; Biophysicial/Biochemical Screening for the Risk of Preterm Labor; Preimplantation Genetic Testing; Toxoplasmosis, Parvovirus and Cytomegalovirus in Pregnancy; and Sleep Apnea and Adverse pregnancy Outcomes.