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Numerous studies have pointed to the key role of complement in the
pathogenesis of retinal disease, particularly age-related macular
degeneration (AMD). Reports about new gene associations and links
to other physiological pathways are emerging almost on a weekly
base. Several promising clinical candidates covering a wide area of
potential treatment applications are in the pipelines of both
industrial and academic groups. This indicates an increasing
interest in complement as a therapeutic target. In view of these
exciting discoveries, scientists from around the world convened at
the First Aegean Conferences Conference on Inflammation and Retinal
Disease: Complement Biology and Pathology (June 10-17, 2007) in
Crete, Greece, to discuss recent advances in this rapidly-evolving
field. This volume represents a collection of topics on the
functions of complement in eye diseases, pathophysiology, protein
structures, and complement therapeutics discussed during the
conference. Our sincere thanks to the contributing authors for the
time and effort they have devoted to writing what I consider
exceptionally informative chapters in a book that will have a
significant impact on the complement field. We would also like to
express my thanks to Rodanthi Lambris for her assistance in
collating the chapters and preparing the documents for publication
and I gratefully acknowledge the generous help provided by
Dimitrios Lambris in managing the organization of this meeting.
Finally, I also thank Andrea Macaluso of Springer Publishers for
her supervision in this book's production. John D. Lambris Anthony
P.
Numerous studies have pointed to the key role of complement in the
pathogenesis of retinal disease, particularly age-related macular
degeneration (AMD). Reports about new gene associations and links
to other physiological pathways are emerging almost on a weekly
base. Several promising clinical candidates covering a wide area of
potential treatment applications are in the pipelines of both
industrial and academic groups. This indicates an increasing
interest in complement as a therapeutic target. In view of these
exciting discoveries, scientists from around the world convened at
the First Aegean Conferences Conference on Inflammation and Retinal
Disease: Complement Biology and Pathology (June 10-17, 2007) in
Crete, Greece, to discuss recent advances in this rapidly-evolving
field. This volume represents a collection of topics on the
functions of complement in eye diseases, pathophysiology, protein
structures, and complement therapeutics discussed during the
conference. Our sincere thanks to the contributing authors for the
time and effort they have devoted to writing what I consider
exceptionally informative chapters in a book that will have a
significant impact on the complement field. We would also like to
express my thanks to Rodanthi Lambris for her assistance in
collating the chapters and preparing the documents for publication
and I gratefully acknowledge the generous help provided by
Dimitrios Lambris in managing the organization of this meeting.
Finally, I also thank Andrea Macaluso of Springer Publishers for
her supervision in this book's production. John D. Lambris Anthony
P.
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