Biological control has become an attractive alternative strategy for the control of plant diseases to reduce the excessive use of agrochemicals and its health hazards. But a significant gap still exists between basic research involving the discovery of a biocontrol agent and its development and implementation under commercial conditions. Because BCAs (unlike chemical a.m.) need to establish, colonize, survive and perform their metabolic activity to control diseases. In order to move a biocontrol agent from the laboratory to the market place requires many different disciplines and people with a variety of expertise. Research can stimulate the development of commercial biocontrol agents. Chapter 16 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.