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Optimization of Pharmaceutical Processes presents contributions
from leading authorities in the fields of optimization and
pharmaceutical manufacturing. Formulated within structured
frameworks, practical examples and applications are given as
guidance to apply optimization techniques to most aspects of
pharmaceutical processes from design, to lab and pilot scale, and
finally to manufacturing. The increasing demand for better quality,
higher yield, more efficient-optimized and green pharmaceutical
processes, indicates that optimal conditions for production must be
applied to achieve simplicity, lower costs and superior yield. The
application of such methods in the pharmaceutical industry is not
trivial. Quality of the final product is of major importance to
human health and the need for deep knowledge of the process
parameters and the optimization of the processes are
imperative. The volume, which includes new methods as well
as review contributions will benefit a wide readership including
engineers in pharmaceuticals, chemical, biological, to name just a
few.
Optimization of Pharmaceutical Processes presents contributions
from leading authorities in the fields of optimization and
pharmaceutical manufacturing. Formulated within structured
frameworks, practical examples and applications are given as
guidance to apply optimization techniques to most aspects of
pharmaceutical processes from design, to lab and pilot scale, and
finally to manufacturing. The increasing demand for better quality,
higher yield, more efficient-optimized and green pharmaceutical
processes, indicates that optimal conditions for production must be
applied to achieve simplicity, lower costs and superior yield. The
application of such methods in the pharmaceutical industry is not
trivial. Quality of the final product is of major importance to
human health and the need for deep knowledge of the process
parameters and the optimization of the processes are imperative.
The volume, which includes new methods as well as review
contributions will benefit a wide readership including engineers in
pharmaceuticals, chemical, biological, to name just a few.
In answer to the unprecedented challenges and threats that face
today’s globalized world, the primary goal of this Handbook is to
identify the most probable threats that have affected humanity in
recent years and our world in years to come. The Handbook comprises
mostly expository chapters that discuss tested methods/algorithms,
case studies, as well as policy decision-making techniques
surrounding threats and unnatural disasters, to evaluate their
effects on people and to propose ways to mitigate these effects.
 In several chapters, new approaches and suggested policies
supplement algorithms that are already in practice. The curated
content brings together key experts from the academic and policy
worlds to formulate a guide of principal techniques employed to
gain better control over selected types of threats. This Handbook
explores a wide range of technologies and theories and their impact
on countering threats. These include artificial intelligence,
machine learning, variational inequality theory, game theory, data
envelopment analysis, and data-driven risk analysis. These tools
play a vital role in decision-making processes and aid in finding
optimal solutions. Additionally, a variety of optimization
techniques are employed. These include (mixed) integer linear
programming models for identifying critical nodes in complex
systems, heuristics, approximation algorithms, and bilevel mixed
integer programming for determining the most impactful links in
dynamic networks. Furthermore, simulation tools are described that
enable the quantification of societal resilience. These techniques
collectively provide a mathematical framework capable of
quantifying fundamental aspects of threats. They equip policymakers
with the necessary tools and knowledge to minimize the impact of
unnatural threats. The expected readership is wide and includes
officials working in technical and policy roles in various
ministries such as the Ministry of Defense, Civil Protection,
Ministry of Public Order and Citizen Protection, United Nations,
European Institutions for Threat Management, NATO, Intelligence
Agencies, Centers of Excellence for Countering Threats, Think
Tanks, Centers for Policy Studies, Political Leaders, the European
Commission, National Institutes, International Organizations,
Strategic Consulting Experts, Policymakers, and Foreign Affairs
personnel. Some of these national or international organizations
employ algorithms to measure resilience and enhance security.
Quantification is challenging but crucial in the scenarios
discussed in the book. This Handbook will also prove valuable to
various universities (non-practitioners), studying systems
engineering, leadership, management, strategy, foreign affairs,
politics, and related disciplines.
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