This book constitutes the proceedings of the 12th International Symposium on Bioinformatics Research and Applications, ISBRA 2016, held in Minsk, Belarus, in June 2016. The 25 papers presented in this volume were carefully reviewed and selected from 77 submissions. They were organized in topical sections named: next generation sequencing data analysis; protein-protein interactions and networks; protein and RNA structure; phylogenetics; sequence analysis; and statistical methods.

This book constitutes the refereed proceedings of the 20th International Conference on Computing and Combinatorics, COCOON 2014, held in Atlanta, GA, USA, in August 2014. The 51 revised full papers presented were carefully reviewed and selected from 110 submissions. There was a co-organized workshop on computational social networks (CSoNet 2014) where 8 papers were accepted. The papers cover the following topics: sampling and randomized methods; logic, algebra and automata; database and data structures; parameterized complexity and algorithms; computational complexity; computational biology and computational geometry; approximation algorithm; graph theory and algorithms; game theory and cryptography; scheduling algorithms and circuit complexity and CSoNet.