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Blood transfusion is considered a life-saving therapy since ancient
times, but, at the same time, a high-risk procedure. Nowadays the
common perception is that infection is the greatest risk, even if
the blood has never been safer from this point of view. Currently,
the residual risk of transfusion must be related mainly to
immunological mechanisms underlying to AB0 and minor blood systems,
to compatibility of blood transfused and to development of
irregular antibodies in transfused patients. "Transfusion Medicine
and Patient Safety" aims to provide the basic of immunohematology
to readers and to analyze the transfusional process highlighting
the most critical points, thus more exposed to errors. Screening on
blood and blood components for infectious diseases along with the
surveillance action on emerging viruses results in the drastic
reduction of post-transfusion infection, together with the
potential to further increase the level of security from infection
through the inactivation of blood components. The text also
describes the major diagnostic systems and organizational models
that modern technology provides us with a correct
immunohematological diagnosis and an appropriate trasfusional
therapy.
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