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The book focuses on the aqueous interface of biomolecules, a vital
yet overlooked area of biophysical research. Most biological
phenomena cannot be fully understood at the molecular level without
considering interfacial behavior. The author presents conceptual
advances in molecular biophysics that herald the advent of a new
discipline, epistructural biology, centered on the interactions of
water and bio molecular structures across the interface. The author
introduces powerful theoretical and computational resources in
order to address fundamental topics such as protein folding, the
physico-chemical basis of enzyme catalysis and protein
associations. On the basis of this information, a
multi-disciplinary approach is used to engineer therapeutic drugs
and to allow substantive advances in targeted molecular medicine.
This book will be of interest to scientists, students and
practitioners in the fields of chemistry, biophysics and biomedical
engineering.
The book focuses on the aqueous interface of biomolecules, a vital
yet overlooked area of biophysical research. Most biological
phenomena cannot be fully understood at the molecular level without
considering interfacial behavior. The author presents conceptual
advances in molecular biophysics that herald the advent of a new
discipline, epistructural biology, centered on the interactions of
water and bio molecular structures across the interface. The author
introduces powerful theoretical and computational resources in
order to address fundamental topics such as protein folding, the
physico-chemical basis of enzyme catalysis and protein
associations. On the basis of this information, a
multi-disciplinary approach is used to engineer therapeutic drugs
and to allow substantive advances in targeted molecular medicine.
This book will be of interest to scientists, students and
practitioners in the fields of chemistry, biophysics and biomedical
engineering.
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