![]() |
![]() |
Your cart is empty |
||
Showing 1 - 1 of 1 matches in All Departments
Scientific interest in regulatory T cells has revived during the
last decade. Initially described in the early seventies as
suppressor T cells, the concept of suppressor/regulatory T cells
went through turbulent times during the eighties when molecular
analysis failed to identify putative suppressor genes. The
constructive and elegant cellular experiments on regulatory T cells
during the nineties, initiated by Shimon Sakaguchi and co-workers,
however have brought these cells back into the limelight. Nowadays,
regulatory T cells are regarded as essential components of the
immune system, and several different subsets of regulatory T cells
have been described. Considerable regulatory function has been
attributed to the CD4+CD25+ T cell subset. These cells act by
suppressing adaptive and possibly also innate immune responses
thereby maintaining or restoring the balance between immunity and
tolerance. The suppressive effects of CD4+CD25+ regulatory T cells
are cell-contact dependent but a role for soluble factors,
particularly in vivo, has been suggested as well.
|
![]() ![]() You may like...
Beauty And The Beast - Blu-Ray + DVD
Emma Watson, Dan Stevens, …
Blu-ray disc
R326
Discovery Miles 3 260
|