Immunofluorescence is a key diagnostic tool in dermatopathology, and essential in the diagnosis of connective tissue diseases, vasculitis and other cutaneous disorders. The need to interpret the results of immunofluorescence testing, and correlate these with histopathological results, is a key skill required not just of dermatopathologists but also, increasingly, of dermatologists who either read the slides themselves or use a pathology lab or academic referral centre. Handbook of Direct Immunofluorescence covers not only day-to-day findings but also less common patterns and rarities, and gives information on important diagnostic pitfalls. Each chapter is dedicated to a specific disease and is introduced by concise text that describes the clinical presentation and pathogenesis: then, multiple images show the range of histopathological and immunofluorescence findings associated with the disease in question. Key points Practical, clinically oriented coverage provides invaluable resource for dermato-, oral and general pathologists, as well as dermatologists Includes invaluable information on technical aspects (specimen procurement, transportation, etc) as well as guidance on interpreting histopathological and immunofluorescence findings Pattern-based approach serves as logical framework for reaching a diagnosis, as well as understanding when to order additional tests and how to recognise nonspecific findings

'You shouldn't drink too much. The Earth is round. Milk is good for your bones.' Are any of these claims true? How can you tell? Can you ever be certain you are right? For anyone tackling philosophical logic and critical thinking for the first time, Critical Thinking: An Introduction to Reasoning Well provides a practical guide to the skills required to think critically. From the basics of good reasoning to the difference between claims, evidence and arguments, Robert Arp and Jamie Carlin Watson cover the topics found in an introductory course. Now revised and fully updated, this Second Edition features a glossary, chapter summaries, more student-friendly exercises, study questions, diagrams, and suggestions for further reading. Topics include: the structure, formation, analysis and recognition of arguments deductive validity and soundness inductive strength and cogency inference to the best explanation truth tables tools for argument assessment informal and formal fallacies With real life examples, advice on graduate school entrance exams and an expanded companion website packed with additional exercises, an answer key and help with real life examples, this easy-to-follow introduction is a complete beginner's tool set to good reasoning, analyzing and arguing. Ideal for students in basic reasoning courses and students preparing for graduate school.

Due to its internationality and interdisciplinarity, the International Oral History Association (IOHA), which was founded in the late 1970's, is one-of-a-kind in the academic landscape. Driven by the desire to democratize historical scholarship, its members wanted to "give a voice" to groups such as women, workers, migrants, or victims of political dictatorships who had not been heard up to that point. The contributions deal with the academic approaches and the political convictions of the previous generation.

What is the nature of Hell? What role(s) may Hell play in religious, political, or ethical thought? Can Hell be justified? This edited volume addresses these questions and others; drawing philosophers from many approaches and traditions to analyze and examine Hell.

In what ways and senses does religion endure? In what ways has development failed Africa? How can we build effective African politics from below? These are some of the questions explored in this volume, which seeks to analyze the shifting and complex sets of relationships that exist between religion, politics and development in Africa. Modernist and secularist thinking has long predicted that religion would be rendered irrelevant, to be sidestepped, ignored or eliminated. However, this is not the case in 21st century Africa. Religion plays an increasingly important role in politics and development. This volume captures the dynamism and power of religion in Africa. In doing so it aims to move beyond narrow conceptualisations of 'politics' and 'development' and public and private spaces in order to uncover the meaning of modern religion in Africa and the many ways it is embedded in millions of Africans' everyday struggles to survive, sustain themselves and make sense of the modern world.

This volume considers the numerous philosophical ideas and arguments found in and inspired by the critically acclaimed series Breaking Bad. This show garnered both critical and popular attention for its portrayal of a cancer-stricken, middle-aged, middle-class, high school chemistry teacher's drift into the dark world of selling methamphetamine to support his family. Its characters, situations, and aesthetic raise serious and familiar philosophical issues, especially related to ethics and morality. The show provokes a bevy of rich questions and discussion points, such as: What are the ethical issues surrounding drugs? What lessons about existentialism and fatalism does the show present? How does the show grapple with the concept of the end 'justifying' the means? Is Walt really free not to 'break bad'? Can he be redeemed? What is the definition and nature of badness (or evil) itself? Contributors address these and other questions as they dissect the legacy of the show and discuss its contributions to philosophical conversations.

Modification of target protein properties by reversible phosphorylation events has been found to be one of the most prominent cellular control processes in all organisms. Recent advances in the areas of molecular biology and biochemistry are presenting new possibilities for reaching an unprecedented depth and a proteome-wide understanding of phosphorylation processes in plants as well as in other species. The major goal of "Plant Kinases: Methods and Protocols" is to provide the experimentalist with a detailed account of the practical steps necessary for successfully carrying out each protocol in his or her own laboratory. Plant protein kinases specifically addressed in this volume are members of the plant MAP kinase cascade, cyclin- and Calcium-dependent protein kinases, and plant sensor and receptor kinases. Written in the highly successful "Methods in Molecular Biology " series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and accessible, "Plant Kinases: Methods and Protocols "will prove a useful laboratory companion to both novice and seasoned researchers by facilitating the practical work that will lead them to new and exciting insights in this dynamic field.

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Stanislavsky and Intimacy is the first academic edited book with a focus on how intimacy protocols, choreography, and theories intersect with the broad practices of Konstantin Stanislavsky’s ‘system’. As the basis for most Western theatre and film acting, Stanislavsky’s system centers on truthful performances. Intimacy direction and choreography insists on not only a culture of consent, but also specific, repeatable choreography for all staged intimate moments. These two practices have often been placed as diametric opposites, but this book seeks to dispel this argument. Each chapter discusses specific Stanislavskian principles and practices as they relate to staged sexually intimate moments, also opening the conversation to the broader themes and practices of other kinds of intimacy within the acting field. Stanislavsky And... is a series of multi-perspectival collections that bring the enduring legacy of Stanislavskian actor training into the spotlight of contemporary performance culture, making them ideal for students, teachers and scholars of acting, actor training, and directing.

‘You shouldn’t drink too much. The Earth is round. Milk is good for your bones.’ Are any of these claims true? How can you tell? Can you ever be certain you are right? For anyone tackling philosophical logic for the first time, here is a practical guide to the skills required to think critically. From the basics of good reasoning to the difference between claims, evidence and arguments, Jamie Carlin Watson, Robert Arp and Skyler King cover the topics found in an introductory course. Now revised and fully updated, this 3rd edition gives you the chance to develop critical thinking skills that can be used in and out of the classroom. Two new chapters on reasoning in the age of conspiracy theories and fake news demonstrate how to apply reason and avoid being dissuaded by the persuasive power of evidence-free emoting. Features include a glossary, chapter goals, more student-friendly exercises, study questions, diagrams, and suggestions for further reading. Chapter topics, organised around real-life examples such as predicting the weather, a murder mystery and the Ouija board, cover: - the structure, formation, analysis and recognition of arguments - deductive validity and soundness - inductive strength and cogency - inference to the best explanation - truth tables - tools for argument assessment - informal and formal fallacies This entertaining and easy-to-follow introduction is a complete beginner’s tool set to good reasoning, analyzing and arguing.

About the Series Mudley the bear belongs to a little girl called Sophia. She lives in a small town in Europe. She would love to travel the world but she has to go to school. And so, each time dad has to leave for work at faraway places, Sophia packs Mudley into his suitcase and tells him Daddy please let Mudley see the world for me" Being narrated by a bear, the series stimulates, excites and educates young people by giving them the culture and heritage of the places they are going to visit and give parents reason to interact with their children. Each location features photographs depicting the area with Mudley in view, a brief outline, illustrations to tell another story and a playful anecdote that will engage the reader. About the Book Mudley Explores Singapore introduces 28 places/activities that will be of interest to young readers. These include the Gardens by the Bay, Sentosa. Kampung Buangkok and the Singapore River and much more. Beautifully illustrated, this book would be an ideal gift or travel souvenir for the young reader.

The Hidden Hypotheses Behind the Big Bang It is quite unavoidable that many philosophical a priori assumptions lurk behind the debate between supporters of the Big Bang and the anti-BB camp. The same battle has been waged in physics between the determinists and the opposing viewpoint. Therefore, by way of introduction to this symposium, I would like to discuss, albeit briefly, the many "hypotheses," essentially of a metaphysical nature, which are often used without being clearly stated. The first hypothesis is the idea that the Universe has some origin, or origins. Opposing this is the idea that the Universe is eternal, essentially without beginning, no matter how it might change-the old Platonic system, opposed by an Aristote lian view Or Pope Pius XII or Abbe Lemaitre or Friedmann versus Einstein or Hoyle or Segal, etc. The second hypothesis is the need for a "minimum of hypotheses" -the sim plicity argument. One is expected to account for all the observations with a mini mum number of hypotheses or assumptions. In other words, the idea is to "save the phenomena," and this has been an imperative since the time of Plato and Aristotle. But numerous contradictions have arisen between the hypotheses and the facts. This has led some scientists to introduce additional entities, such as the cosmologi cal constant, dark matter, galaxy mergers, complicated geometries, and even a rest mass for the photon. Some of the proponents of the latter idea were Einstein, de Broglie, Findlay-Freundlich, and later Vigier and myself."

Stanislavsky and Intimacy is the first academic edited book with a focus on how intimacy protocols, choreography, and theories intersect with the broad practices of Konstantin Stanislavsky’s ‘system’. As the basis for most Western theatre and film acting, Stanislavsky’s system centers on truthful performances. Intimacy direction and choreography insists on not only a culture of consent, but also specific, repeatable choreography for all staged intimate moments. These two practices have often been placed as diametric opposites, but this book seeks to dispel this argument. Each chapter discusses specific Stanislavskian principles and practices as they relate to staged sexually intimate moments, also opening the conversation to the broader themes and practices of other kinds of intimacy within the acting field. Stanislavsky And... is a series of multi-perspectival collections that bring the enduring legacy of Stanislavskian actor training into the spotlight of contemporary performance culture, making them ideal for students, teachers and scholars of acting, actor training, and directing.

In contradistinction to the many monographs and edited volumes devoted to historical, cultural, or theological treatments of demonology, this collection features newly written papers by philosophers and other scholars engaged specifically in philosophical argument, debate, and dialogue involving ideas and topics in demonology. The contributors to the volume approach the subject from the perspective of the broadest areas of Western philosophy, namely metaphysics, epistemology, logic, and moral philosophy. The collection also features a plurality of religious, cultural, and theological views on the nature of demons from both Eastern and Western thought, in addition to views that may diverge from these traditional roots. Philosophical Approaches to Demonology will be of interest to philosophers of religion, theologians, and scholars working in philosophical theology and demonology, as well as historians, cultural anthropologists, and sociologists interested more broadly in the concept of demons.

This collection brings together new papers addressing the philosophical challenges that the concept of a Devil presents, bringing philosophical rigor to treatments of the Devil. Contributors approach the idea of the Devil from a variety of philosophical traditions, methodologies, and styles, providing a comprehensive philosophical overview that contemplates the existence, nature, and purpose of the Devil. While some papers take a classical approach to the Devil, drawing on biblical exegesis, other contributors approach the topic of the Devil from epistemological, metaphysical, phenomenological, and ethical perspectives. This volume will be relevant to researchers and scholars interested in philosophical conceptions of the Devil and related areas, such as philosophers of religion, theologians, and scholars working in philosophical theology and demonology.

This book seeks to explore welfare responses by questioning and going beyond the assumptions found in Esping-Andersen's broad typologies of welfare capitalism. Specifically, the project seeks to reflect how the state engages, and creates general institutionalized responses to, market mechanisms and how such responses have created path dependencies in how states approach problems of inequality. Moreover, if the neoliberal era is defined as the dissemination and extension of market values to all forms of state institutions and social action, the need arises to critically investigate not only the embeddedness of such values and modes of thought in different contexts and institutional forms, but responses and modes of resistance arising from practices that might point to new forms of resilience.

This book engages the problem of evil from a variety of philosophical viewpoints, traditions, methodologies, and interests. For millennia, philosophers, theologians, and people outside of the academy have thought about evil and its relation to religious belief. The Problem of Evil: New Philosophical Directions aims to take this history of thought into evil while also extending the discourse in other directions; providing a multi-faceted collection of papers that take heed of the various ways one can think about evil and what role in may play in philosophical considerations of religion. From the nature of evil to the well-known problem of evil to the discussion of the problem in philosophical discourse, the collection provides a wide range of philosophical approaches to evil. Anyone interested in evil-its nature, relation to religious belief, its use in philosophical discussion, and so on-will find the papers in this book of interest.