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Ocular transporters and receptors contains detailed descriptions of
major transporters and receptors expressed in the eye, with special
emphasis on their role in drug delivery. The complex anatomy and
the existence of multiple barriers in the eye pose a considerable
challenge to successful drug delivery to the eye. Hence ocular
transporters and receptors are important targets for drug delivery.
A significant advancement has been made in the field of ocular
transport research and their role in drug delivery. In this book
the cutting edge research being carried out in this field is
compiled and summarized. The book focuses on key areas, including
the anatomy and physiology of the eye, biology of ocular
transporters and receptors, techniques in characterization of
transporters and receptors, transporters and receptors in the
anterior and posterior segment in the eye, the role of ocular
transporters and receptors in drug delivery, and
transporter-metabolism interplay in the eye.
Highly focused on ocular transportersMost up-to-date research
compilationDetailed description of role of transporters and
receptors in ocular drug discovery and delivery
The second edition of this text assembles significant ophthalmic
advances and encompasses breakthroughs in gene therapy, ocular
microdialysis, vitreous drug disposition modelling, and
receptor/transporter targeted drug delivery.
Extensively revised and updated, this second edition compares
conventional and innovative drug delivery systems. The book covers
significant ophthalmic advances and breakthroughs in gene therapy,
ocular microdialysis, vitreous drug disposition modelling, and
receptor/transporter targeted drug delivery. It examines procedures
in pharmacokinetic/pharmacodynamic modeling for the determination
of appropriate dosing regimens, covers new developments in animal
modeling, and discusses current regulations governing patenting,
commercial product release, and human testing. This in-depth
reference lays the groundwork for overcoming constraints on the
delivery of ophthalmic drugs.
Emerging Nanotechnologies for Diagnostics, Drug Delivery and
Medical Devices covers the modern micro and nanotechnologies used
for diagnosis, drug delivery, and theranostics using micro, nano,
and implantable systems. In-depth coverage of all aspects of
disease treatment is included. In addition, the book covers
cutting-edge research and technology that will help readers gain
knowledge of novel approaches and their applications to improve
drug/agent specificity for diagnosis and efficient disease
treatment. It is a comprehensive guide for medical specialists, the
pharmaceutical-industry, and academic researchers discussing the
impact of nanotechnology on diagnosis, drug delivery, and
theranostics.
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