This textbook comprehensively covers mechanical ventilation in neonates and children integrating the latest knowledge and understanding of developmental biology, age-related and disease-specific physiologic differences in the practice of mechanical ventilation. The physiology associated with ventilation and lung mechanics are described. Guidance is provided on how to carry out a range of clinical assessments appropriately, including those for ventilation, mechanics and breathing control. Available pathophysiology-based management strategies for a range of situations including respiratory failure and ventilatory failure are also provided. Mechanical Ventilation in Neonates and Children: A Pathophysiology Based Management Approach broadly covers a range of topics associated with mechanical ventilation in children and neonates. It is a valuable resource for specific seminars or courses that concentrate on respiratory failure in children and for those preparing for board certification examinations for neonatal/perinatal medicine and pediatric critical care medicine.