|
Showing 1 - 10 of
10 matches in All Departments
In last few decades interest of researcher and peoples were
augmented in cosmetics. Harmful effect of chemicals used in
cosmetic preparation gives rise to herbal products in cosmetology.
Unlike chemical based products, herbs are by nature more friendly
to human body and therefore are completely safe, extremely
effective and have almost no negative side effects. They are used
in cosmetic for enhancing attractiveness and cleaning purpose.
Beside this the standardization of the herbs and quality control of
the herbs are very necessary in the cosmetic. Hence the book
focuses on the potential of herbal extract for cosmetic purpose.
More sophisticated formulation containing herbal extracts are
expected to appear in the future as cosmetic and various challenges
which may affect quality of herbal products. It also enlightens
various compendia's standardization techniques which effectively
control the quality of herbal cosmetics.
In current drug discovery and development field bioanalytical
techniques plays an important role in quantitative determination in
plasma. Various pharmacokinetics, toxicokinetics, bioequivalence
and exposure-response (pharmacokinetics/ pharmacodynamics) are
biomedical drug development pursuits that cannot be accomplished
without an accurate means of quantifying the moieties that
scientists seek to characterize. Many chromatographic techniques
immensely used for this. Hence this book comprehensively gives an
overview on various important aspects and challenges in
bioanalytical techniques. Beside this it also enlighten
bioanalytical method validation which gives regulatory requirement
for any process.
The resistance of malaria parasites to widely used drugs prompted
an upsurge in the development of new drugs with novel mechanism of
action, and re- evaluation of the existing drugs to overcome the
resistance problem. A number of new potential target pathways have
already been identified and efforts to develop lead compounds for
these putative targets hopefully will allow treatment of malaria
infections in a uniform sustained way. Considerable research
efforts were directed in the areas of chloroquine drug resistance
reversal agents. Careful development of some bisquinolines, which
are free of toxic side effect, 4-anilinoquinolines and modified
chloroquine analogs may be helpful to obtain drug candidates that
inhibit the growth of chloroquine sensitive and resistant
parasites. In the past several years, new structural classes of
antimalarial agents, target based antimalarial agents, iron
chelators have made some interesting and promising lead molecules
available for further optimization to provide compounds for
clinical development.
Pulsatile Drug Delivery Systems are gaining a lot of interest as
these systems deliver the drug at specific time as per the
pathophysiological need of the disease, thus providing spatial and
temporal delivery and increasing patient compliance. Diseases
wherein such delivery systems are promising include asthma, peptic
ulcer, cardiovascular diseases, arthritis, attention deficit
syndrome in children, and hypercholesterolemia. This book will
cover various approaches that have been developed to control drug
delivery profile with different polymeric systems like time
controlling, internal stimuli induced (temperature induced and
chemical stimuli-induced), external induced (magnetic fields,
ultrasound, electric fields and light stimulation) and
Multiparticulate system. Special attention have been made towards
recent advances, patents, future opportunity and major challenges
regarding formulation of pulsatile drug delivery of oral dosage
forms and are summarized and discussed.
|
|