The proceedings of the 2022 edition of the International Symposium of Robotics Research (ISRR) offer a series of peer-reviewed chapters that report on the most recent research results in robotics, in a variety of domains of robotics including robot design, control, robot vision, robot learning, planning, and integrated robot systems. The proceedings entail also invited contributions that offer provocative new ideas, open-ended themes, and new directions for robotics, written by some of the most renown international researchers in robotics. As one of the pioneering symposia in robotics, ISRR has established some of the most fundamental and lasting contributions in the field since 1983. ISRR promotes the development and dissemination of ground-breaking research and technological innovation in robotics useful to society by providing a lively, intimate, forward-looking forum for discussion and debate about the status and future trends of robotics, with emphasis on its potential role to benefit humans.