The four synthetic compounds named Ortho-amino aniline, 2-bromo propyl amine hydrobromide, 3-bromopopyl ammonium bromide and Benzimidazole-2-thiol were evaluated for their pharmacological activity. Evaluation of anti-oxidant activity was done by DPPH free radical scavenging activity. In this investigation, the compound ortho amino aniline showed the highest free radical scavenging activity with IC50 value 0.85 g/ml. At the same time Benzimadazole-2-Thiol also showed strong antioxidant potential having IC50 value 4.18 g/ml. The cyto-toxic activity was evaluated using Brine shrimp lethality bio-assay. Among the supplied compounds only ortho amino aniline and bennzimidazole-2-thiol showed mild cyto-toxic activity compared to the positive standard Vincristine sulfate. The analgesic activity was evaluated using acetic acid induced writhing method. The compounds Benzimidazole-2-thiol and 3-bromopopyl ammonium bromide at a dose of 50 mg/kg showed significant analgesic activity with 37.85% and 42.85% inhibition of writhing. 3-bromopopyl ammonium bromide and Benzimidazole-2-thiol showed mild hypnotic activity. None of the compounds exhibited anti-microbial or ani-pyretic activity."

The crude methanolic extract and different fractions of plant Boerhavia repens were subjected to a number of biological tests for the evaluation of their pharmacological activity.The whole plant of Boerhavia repens was extracted with methanol by cold extraction method. The concentrated extract of the plant were then partitioned into pet ether, carbon tetrachloride, dichloromethane and ethyl acetate soluble fractions.The carbon tetrachloride, dichloromethane and the ethyl acetate soluble fractions of the plant showed strong anti-oxidant activity. The cytotoxicity evaluation of the plant extracts were carried out by Brine Shrimp Lethality Bioassay. The pet ether soluble fractions of the plant showed strong cytotoxic activity. The crude methanolic extract and pet ether soluble fraction at doses of 400 mg/kg exhibited strong analgesic activity, anti-inflammatory and anti-pyretic activity. The different fractions and the crude methanolic extract were also subjected to anti-microbial assay. However no fractions exhibited strong anti-microbial activity.