This volume constitutes the refereed proceedings of the 12th International Conference on Computational Collective Intelligence, ICCCI 2020, held in Da Nang, Vietnam, in November 2020.*The 70 full papers presented were carefully reviewed and selected from 314 submissions. The papers are grouped in topical sections on: knowledge engineering and semantic web; social networks and recommender systems; collective decision-making; applications of collective intelligence; data mining methods and applications; machine learning methods; deep learning and applications for industry 4.0; computer vision techniques; biosensors and biometric techniques; innovations in intelligent systems; natural language processing; low resource languages processing; computational collective intelligence and natural language processing; computational intelligence for multimedia understanding; and intelligent processing of multimedia in web systems. *The conference was held virtually due to the COVID-19 pandemic.