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Lead is an environmental toxic metal, which is capable of causing
many chronic diseases. Important sources of lead include pipes,
lead containing paints, gasoline containing lead, and the different
kinds of canned foods. In the present study lead toxicity and the
oxidative stress caused by lead intoxication has been studied.
Oxidative stress is a very major effect of lead. The mechanism of
lead-induced oxidative stress involves an imbalance between
generation and removal of ROS (reactive oxygen species) in tissues
and cellular components causing damage to membranes, DNA and
proteins. The blood samples from lead exposed and control males
were collected and sera was isolated from them. Different
biochemical tests were performed on serum by the use of biochemical
kits. The results indicated an increase in glucose concentration in
lead exposed subjects.
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