With the detailed genomic information that is now becoming available, we have a plethora of data that allows researchers to address questions in a variety of areas. Genome-wide association studies (GWAS) have become a vital approach to identify candidate regions associated with complex diseases in human medicine, production traits in agriculture, and variation in wild populations. Genomic prediction goes a step further, attempting to predict phenotypic variation in these traits from genomic information. Genome-Wide Association Studies and Genomic Prediction pulls together expert contributions to address this important area of study. The volume begins with a section covering the phenotypes of interest as well as design issues for GWAS, then moves on to discuss efficient computational methods to store and handle large datasets, quality control measures, phasing, haplotype inference, and imputation. Later chapters deal with statistical approaches to data analysis where the experimental objective is either to confirm the biology by identifying genomic regions associated to a trait or to use the data to make genomic predictions about a future phenotypic outcome (e.g. predict onset of disease). As part of the Methods in Molecular Biology series, chapters provide helpful, real-world implementation advice.

With the detailed genomic information that is now becoming available, we have a plethora of data that allows researchers to address questions in a variety of areas. Genome-wide association studies (GWAS) have become a vital approach to identify candidate regions associated with complex diseases in human medicine, production traits in agriculture, and variation in wild populations. Genomic prediction goes a step further, attempting to predict phenotypic variation in these traits from genomic information. Genome-Wide Association Studies and Genomic Prediction pulls together expert contributions to address this important area of study. The volume begins with a section covering the phenotypes of interest as well as design issues for GWAS, then moves on to discuss efficient computational methods to store and handle large datasets, quality control measures, phasing, haplotype inference, and imputation. Later chapters deal with statistical approaches to data analysis where the experimental objective is either to confirm the biology by identifying genomic regions associated to a trait or to use the data to make genomic predictions about a future phenotypic outcome (e.g. predict onset of disease). As part of the Methods in Molecular Biology series, chapters provide helpful, real-world implementation advice.

While the world's scientists and many of its inhabitants despair at the impact of climate change, corporate and military leaders see nothing but opportunities. For them, melting ice caps mean newly accessible fossil fuels, borders to be secured from 'climate refugees', social conflicts to be managed and more failed states in which to intervene. They are 'securing' their assets at the expanse of the planet and its inhabitants. The Secure and the Dispossessed looks at these deadly approaches with a critical eye. It also considers the flip-side: that the legitimacy of the elite is under unprecedented pressure - from resistance by communities to resource grabs to those creating new ecological and socially just models for managing our energy, food and water. Topics covered include geoengineering, militarism, refugee protection, greenwashing and the agricultural crisis among others. Adaptation and resilience to a climate-changed world is desperately needed, but the form it will take will affect all of our futures.

While the world's scientists and many of its inhabitants despair at the impact of climate change, corporate and military leaders see nothing but opportunities. For them, melting ice caps mean newly accessible fossil fuels, borders to be secured from 'climate refugees', social conflicts to be managed and more failed states in which to intervene. They are 'securing' their assets at the expanse of the planet and its inhabitants. The Secure and the Dispossessed looks at these deadly approaches with a critical eye. It also considers the flip-side: that the legitimacy of the elite is under unprecedented pressure - from resistance by communities to resource grabs to those creating new ecological and socially just models for managing our energy, food and water. Topics covered include geoengineering, militarism, refugee protection, greenwashing and the agricultural crisis among others. Adaptation and resilience to a climate-changed world is desperately needed, but the form it will take will affect all of our futures.