Former FBI agent Will Graham (William Petersen), who specialises in catching serial killers, is brought out of early retirement to track down a murderer who bludgeons entire families only when the moon is full. Graham's tactic is to enter the mind of the deranged criminal, which turns out to have an enormous emotional strain attached. When he seeks advice from imprisoned psychiatrist/psychopath Dr Lecter (Brian Cox), he ends up endangering himself and his family. Based on the novel which was the precursor to 'Silence of the Lambs'. The 18-minute bonus feature 'Inside Manhunter' is also included.