The beautiful and tragic saga of the Louvin Brothers - one of the most legendary country duos of all time - is one of America's great untold stories. Charlie Louvin was a good, god-fearing, churchgoing singer, but his brother Ira had the devil in him and was known for smashing his mandolin to splinters onstage, cussing out Elvis Presley, and trying to strangle his third wife with a telephone cord. "Satan is Real" is the incredible tale of Charlie Louvin's sixty-five-year career, the timeless murder ballads of the Louvin Brothers, and the epic tale of two brothers bound together by love, hate, alcohol, blood, and music.

Douglas Pike is no longer the murderous hustler he was in his youth, but reforming hasn't made him much kinder. He's just living out his life in his Appalachian hometown, working odd jobs with his partner, Rory, hemming in his demons the best he can. And his best seems just good enough until his estranged daughter overdoses, and he takes in his 12-year-old granddaughter, Wendy. Just as the two are beginning to forge a relationship, Derrick Kreiger, a dirty Cincinnati cop, starts to take an unhealthy interest in the girl. Pike and Rory head to Cincinnati to learn what they can about Derrick and the death of Pike's daughter, and the three men circle, evenly matched predators in a human wilderness of junkie squats, roadhouse bars, and homeless Vietnam vet encampments.