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150 years after the first description of the clinical picture of
"white blood" and the introduction of the term "leukemia" by R.
Virchow it appears, that the leukemias, and the acute leukemias in
particular, serve as an impressive example for the major
improvements that have been achieved in the treatment but also in
the understand ing of the biology of malignant dis orders. The
international symposia "Acute Leukemia" which are held at Munster
since 1986 have developed into an interna tional forum to review
the current progress and the future perspectives of leukemia
research and therapy at a high scientific and clinicallevel. Since
the possibility for active participation in these symposia is
somewhat restricted we are glad to have the opportunity to extend
the information that was presented at the symposium "Acute
Leukemias V - Experimental Approaches and Management of Refractory
Disease" which was held from February 27 to March 2, 1994 to a
broader audience of basic scientists and clinicians. This meeting
was especiaIly designed to discuss experimen tal approaches and the
management of refractory disease which allows to evaluate new
experimental therapies on the basis of preclinical studies."
The 6th volume of the book series Acute Leukemias presents both
therapeutic and prognostic updates of the most recent results of
major multicenter clinical trials. Additional chapters report on
new trends in leucemia cell biology, the monitoring of minimal
residual disease and secondary leucemias as well as new
antileucemic drugs, antimicrobial strategies and the use of
cytocines. Acute Leukemias VI provides a new update on the rapid
progress being made internationally concerning leucemic diseases.
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