The present study was planned on prepubertal female rats to evaluate the mechanism of cadmium-induced toxicity and to evaluate the prophylactic and the therapeutic potential of Saraca indica against cadmium-induced oxidative stress in female reproductive system with the following objectives. 1) To study the mechanisms of toxicity of cadmium on female reproductive system of prepubertal rats. 2) To study the protective role of Saraca indica against cadmium induced damage to in prepubertal rats.