|
Showing 1 - 8 of
8 matches in All Departments
Activities and biological relationships of terpenes. An accurate
assessment of where and what terpenes can lead to. Discusses how
microbes, in particular the actinomycetales, have well over 400
different gene clusters that produce terpenes. Arranged by
biological activities and usage. Provides information on eukaryotic
enzymes that have been shown to be a source of "ethnobotanical"
terpenes
Tellurium, a well-known chalcogen, finds potential applications in
various fields from chemistry to other branches of science such as
nanotechnology and macromolecular science. However, its safety must
also be taken into consideration when exploring its industrial
applications. This book explores the breadth of tellurium's
applications, outlines strategies for industrial use, and describes
the safety concerns of this element.
Cancer is an incredibly diverse and difficult disease to treat, and
even after decades of research there is no definitive cure.
Therefore, it is highly crucial to search for novel and new organic
molecules with high potency, low toxicity, and low mutagenicity
with selective anticancer properties that are able to overcome
frequently developed resistance to available drugs. Heterocyclic
anticancer agents are an important class of drugs for cancer
therapies. This book explores different heterocycles and their use
as anticancer therapies. Topics covered include different
heterocyclic derivatives, the impact of heterocycles on anticancer
agent development, and naturally occurring heterocycles.
Organocatalysis are an important tool for greener catalytic
processes due to the lack of precious metals used. This book
explores different organocatalysts and their use in synthesis.
Topics covered include zwitterionic imidazolium salt catalysts,
asymmetric catalysts in aqueous media, beaker yeast catalysis,
organocatalysts for Aldol and Michael reactions, amino acid-based
organocatalysts, and Broensted acidic surfactant organocatalysts.
Extensive experimentation and high failure rates are a
well-recognized downside to the drug discovery process, with the
resultant high levels of inefficiency and waste producing a
negative environmental impact. Sustainable and Green Approaches in
Medicinal Chemistry 2e reveals how medicinal chemistry can play a
direct role in addressing this issue. After providing essential
context to the growth of green chemistry in relation to drug
discovery, the book goes on to identify a broad range of practical
techniques and useful insights, revealing how medicinal chemistry
techniques can be used to improve efficiency, mitigate failure and
increase the environmental benignity of the entire drug discovery
process. Drawing on the knowledge of a global team of experts,
Sustainable and Green Approaches in Medicinal Chemistry, Second
Edition encourages the growth of green medicinal chemistry,
and supports medicinal chemists, drug discovery researchers,
pharmacologists and all those in related fields across both
academia and industry in integrating these approaches into their
own work. This second volume of the second edition includes the
development of nanoparticles and nanocomposites, as well as the
application of ultrasound and microwave-induced methods; studies
solventless synthesis; defines the role of steroids; studies
reactions in aqueous solution; identifies enzyme-mediated
reactions; investigates ionic liquids and deep eutectic solvents;
explores natural products; investigates solid supports; realizes
the effects of salts; focuses on combinatorial chemistry; develops
one-pot methods; analyzes multi-component reactions; investigates
dipole moment values; and examines computer-assisted methods.
Extensive experimentation and high failure rates are a
well-recognised downside to the drug discovery process, with the
resultant high levels of inefficiency and waste producing a
negative environmental impact. Sustainable and Green Approaches in
Medicinal Chemistry, Second Edition reveals how medicinal chemistry
can play a direct role in addressing this issue. After providing
essential context to the growth of green chemistry in relation to
drug discovery, the book goes on to identify a broad range of
practical techniques and useful insights, revealing how medicinal
chemistry techniques can be used to improve efficiency, mitigate
failure and increase the environmental benignity of the entire drug
discovery process. Drawing on the knowledge of a global team of
experts, Sustainable and Green Approaches in Medicinal Chemistry 2e
encourages the growth of green medicinal chemistry, and supports
medicinal chemists, drug discovery researchers, pharmacologists and
all those in related fields across both academia and industry in
integrating these approaches into their own work. This first volume
of the second edition covers synthesis methods following green
chemistry principles, contributing to sustainability by saving
energy, using lesser toxic reagents/solvents/catalysts and
environmentally benign sources including plants and agricultural
materials.
Natural Products as Anticancer Agents introduces the different
types of natural products that have been used for cancer treatment.
Divided into four parts, covering anticancer agents derived from
terrestrial plants, anticancer agents derived from the marine
environment, and anticancer agents derived from microorganisms, as
well as evaluation of new anticancer agents, each part includes
discussion of the properties, synthesis/extraction, storage,
mechanism of action, and usage of the molecules. Discussion of the
future prospects in anticancer natural products—including several
new trends and an indication of where research in this area is
likely to go in the future—is also included.
Organic and medicinal chemistry are definitely the principal
branches of chemistry as they are more widely studied than any
other subjects in chemistry. Very often, organic and medicinal
chemistry have been defined as a hybrid discipline of many other
subjects that include biology, chemistry, medicine and pharmacy.
The synthesis of molecules, mechanism of a process, studies of new
reagents, natural products, biological and pharmacological
evaluation of molecules against different components of cells are
the key subjects in these two areas. On the basis of unlimited
possibilities, one can imagine several scopes exist for students,
researchers and industrialists to study and explore organic and
medicinal chemistry. In this book, an attempt has been made to
include diverse research topics to benefit the readers from
different standpoints. This book has nine chapters (Volume 2) from
active authors. Bhalla and his group have written two chapters in
this volume. In the first chapter, Berry and Bhalla have
demonstrated recent progress on the pharmacological profile of
pyrazole and imidazole conjugates. In the second chapter, Kumari
and Bhalla have explored the synthesis of optically active beta
lactams. Sahoo and Banik have explored new quinazolines synthesis
and their medicinal and pharmacological properties in Chapter
Three. Perchyonok has described natural biomaterials for veterinary
therapy through an in vitro approach in the fourth chapter. In the
fifth chapter, Perchyonok et al. have also reported studies on
cytotoxicity biomaterials containing chitosan hydrogels. Philips
has demonstrated the synthesis and applications of
pharmacologically relevant phosphonates and phosphinites in Chapter
Six. Basu and Banik have explored apoptosis in the inhibition of
cancer in Chapter Seven. Maji and Ganguly have demonstrated the use
of mushrooms as a food in Chapter Eight. Bandyopadhyay et al. have
studied key enzymes that are responsible in cancer and their
mechanism of action in the ninth chapter. Scientists are convinced
that organic and medicinal chemistry have no boundaries in science.
The application of these chemical and medicinal sciences is huge
and they are related to many significant discoveries. On this
basis, the book will be useful for chemists, biologists,
clinicians, pharmacists, biotechnologists, industrialists and
engineers who are working in the field of interdisciplinary science
as well as specific chemical and medicinal science.
|
You may like...
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
|