Infrared and Raman Spectroscopy of Biological Materials facilitates a comprehensive and through understanding of the latest developments in vibrational spectroscopy. It contains explains key breakthroughs in the methodologies and techniques for infrared, near-infrared, and Raman spectroscopy. Topics include qualitative and quantitative analysis, biomedical applications, vibrational studies of enzymatic catalysis, and chemometrics.

"Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial library--by determining the usefulness of synthesized compunds, the reliability of biological assay results, and analyzing acadmic and industrial applications, real-world examples, and case studies of successful and unsuccessful technologies."

Since the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened focus on select areas, Analytical Methods in Combinatorial Chemistry, Second Edition updates a classic text and captures the current state of these technologies. Written by leaders in the field, this second edition includes several enhancements. A chapter on high-throughput analytical methods and informatics reflects the demand for quality control of library members. A new chapter focuses on high-throughput purification methods. All chapters have been updated with new data. Topics discussed in this second edition include: Properties of solid-phase samples, analytical studies targeted to understand these properties, and resin swelling Fourier Transform Infrared techniques On-support mass spectrometry and nuclear magnetic resonance methods used in the reaction optimization stage Combinatorial library analysis using spectrophotometric, fluorometric, and other methods Quality control of combinatorial libraries High-throughput purification methods Future directions and analytical challenges The coming decade is sure to usher in a new wave of progress in this critical field. This volume provides not only an analysis of the recent developments in analytical methods, technologies and applications; it also provides a window on future possibilities.

"Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial library--by determining the usefulness of synthesized compunds, the reliability of biological assay results, and analyzing acadmic and industrial applications, real-world examples, and case studies of successful and unsuccessful technologies."

This book brings together reviews from international experts who are exploring the biological activities of nanomaterials for medical applications or to better understand nanotoxicity. Topics include but are not limited to the following: 1) mechanistic understanding of nanostructure-bioactivity relationships; 2) the regulation of nanoparticles' bioactivity by means of chemical modification; 3) the new methodologies and standard methods used to assess nanoparticles' bioactivity; 4) the mechanisms involved in nanoparticle-biomolecule interactions and nanoparticle-cell interactions; and 5) biomedical applications of nanotechnology. The book will be a valuable resource for a broad readership in various subfields of chemical science, engineering, biology, environment, and medicine.

This book presents the main research advances in the field of photofunctional rare earth hybrid materials. The first chapter discusses the fundamental principles, ranging from rare earth, rare earth luminescence, luminescent rare earth compounds and photofunctional rare earth hybrid materials. The main body of the book consists of six chapters exploring different kinds of photofunctional hybrid materials, such as hybrids based on organically modified silica; organically modified mesoporous silica; functionalized microporous zeolite and metal-organic frameworks; polymer or polymer/silica composite; and multi-component assembly of hybrids. It also includes a chapter introducing the photofunctional application of these hybrid materials. It is a valuable resource for a wide readership in various fields of rare earth chemistry, chemical science and materials science.

This book brings together reviews from international experts who are exploring the biological activities of nanomaterials for medical applications or to better understand nanotoxicity. Topics include but are not limited to the following: 1) mechanistic understanding of nanostructure-bioactivity relationships; 2) the regulation of nanoparticles' bioactivity by means of chemical modification; 3) the new methodologies and standard methods used to assess nanoparticles' bioactivity; 4) the mechanisms involved in nanoparticle-biomolecule interactions and nanoparticle-cell interactions; and 5) biomedical applications of nanotechnology. The book will be a valuable resource for a broad readership in various subfields of chemical science, engineering, biology, environment, and medicine.

Rare Earth Metal-Organic Framework Hybrid Materials for Luminescence Responsive Chemical Sensors primarily focuses on rare earth functionalized metal-organic framework (MOF) hybrid materials for sensing applications. Sections cover an introduction to the field and key concepts like luminescence, rare earth ion luminescence and luminescence response for chemical sensing. Other section emphasize the luminescence response mode and sensing mechanisms of these important materials, including single mode and dual mode sensing, as well as chemical sensing mechanisms. Final sections outline different kinds of sensing analytes by rare earth functionalized MOFs hybrids and delve into emerging application. This book is suitable for materials scientists and engineers, materials chemists, chemists and chemical engineers. In addition, the material is appropriate for those working in academia and R&D in industry.

Since the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened focus on select areas, Analytical Methods in Combinatorial Chemistry, Second Edition updates a classic text and captures the current state of these technologies. Written by leaders in the field, this second edition includes several enhancements. A chapter on high-throughput analytical methods and informatics reflects the demand for quality control of library members. A new chapter focuses on high-throughput purification methods. All chapters have been updated with new data. Topics discussed in this second edition include: Properties of solid-phase samples, analytical studies targeted to understand these properties, and resin swelling Fourier Transform Infrared techniques On-support mass spectrometry and nuclear magnetic resonance methods used in the reaction optimization stage Combinatorial library analysis using spectrophotometric, fluorometric, and other methods Quality control of combinatorial libraries High-throughput purification methods Future directions and analytical challenges The coming decade is sure to usher in a new wave of progress in this critical field. This volume provides not only an analysis of the recent developments in analytical methods, technologies and applications; it also provides a window on future possibilities.