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In a rapidly evolving and extremely important area of medical
science, it is often difficult for the student, teacher, and
researcher to keep abreast of all the important advances. The
purpose of Molecular Biology ofDiabetes, Parts I and II is to bring
to these individuals the latest knowledge of diabetes-related
research in a comprehensive, yet concise manner. To this end, we
have assembled chapters, written by most of the world's experts in
the field, that we believe compre hensively survey and synthesize a
coherent understanding of the subject. Studies of the etiology of
type I and type II diabetes are extremely exciting and essential,
since we hope to one day prevent the disease using gene therapy.
These aspects are covered in Molecular Biology of Diabetes: I.
Autoimmunity and Genetics; Insulin Synthesis and Secretion. In type
II diabetes, an abnormality in pancreatic secretion exists
concomitantly with peripheral insulin resistance. This abnor mality
of insulin secretion is believed to be related to a defect(s) in
glucose sensing. Uncoupling of glucose sensing from insulin secre
tion may be the crucial step in the pathogenesis of
noninsulin-depen dent diabetes. In this volume, we have invited
authors to describe their studies on all known factors affecting
~-cell function, including autoimmunity and genetics of diabetes,
as well as molecular mecha nisms of insulin synthesis and
secretion. In the last few years, the most rapidly advancing area
of research in diabetes has been, in fact, related to insulin
action.
An unprecedented compilation of state-of-the-art advances in
clinical research by premier clinical scientists around the world.
This volume discusses the methods of clinical research and the
interpretation of their results in studies of normal individuals,
obese subjects, and patients with diabetes mellitus. Along the way,
the authoritative contributors writing here illuminate how changes
in the hormone action and substrate metabolism of healthy humans
may lead to obesity and noninsulin-dependent diabetes mellitus.
An unprecedented compilation of state-of-the-art advances in
clinical research by premier clinical scientists around the world.
This volume discusses the methods of clinical research and the
interpretation of their results in studies of normal individuals,
obese subjects, and patients with diabetes mellitus. Along the way,
the authoritative contributors writing here illuminate how changes
in the hormone action and substrate metabolism of healthy humans
may lead to obesity and noninsulin-dependent diabetes mellitus.
In a rapidly evolving and extremely important area of medical
science, it is often difficult for the student, teacher, and
researcher to keep abreast of all the important advances. The
purpose of Molecular Biology ofDiabetes, Parts I and II is to bring
to these individuals the latest knowledge of diabetes-related
research in a comprehensive, yet concise manner. To this end, we
have assembled chapters, written by most of the world's experts in
the field, that we believe compre hensively survey and synthesize a
coherent understanding of the subject. Studies of the etiology of
type I and type II diabetes are extremely exciting and essential,
since we hope to one day prevent the disease using gene therapy.
These aspects are covered in Molecular Biology of Diabetes: I.
Autoimmunity and Genetics; Insulin Synthesis and Secretion. In type
II diabetes, an abnormality in pancreatic secretion exists
concomitantly with peripheral insulin resistance. This abnor mality
of insulin secretion is believed to be related to a defect(s) in
glucose sensing. Uncoupling of glucose sensing from insulin secre
tion may be the crucial step in the pathogenesis of
noninsulin-depen dent diabetes. In this volume, we have invited
authors to describe their studies on all known factors affecting
-cell function, including autoimmunity and genetics of diabetes, as
well as molecular mecha nisms of insulin synthesis and secretion.
In the last few years, the most rapidly advancing area of research
in diabetes has been, in fact, related to insulin action."
These comprehensive yet concise collections of articles by world
experts survey the latest findings on the molecular biology of
diabetes and insulin action and synthesize a coherent understanding
of the subject. Topics include the etiology of type I and type II
diabetes, molecular and cellular aspects of insulin action, and the
mechanism of the insulin-stimulated glucose uptake.
An unprecedented compilation of state-of-the-art advances in
clinical research on diabetes and obesity by premier clinical
scientists around the world. This volume critically reviews the
limitations and strengths of today's major techniques in clinical
diabetes research, and then reviews how those methods have been
used to carry out cutting-edge studies of carbohydrate, lipid, and
protein metabolism in the disease.
An unprecedented compilation of state-of-the-art advances in
clinical research on diabetes and obesity by premier clinical
scientists around the world. This volume critically reviews the
limitations and strengths of today's major techniques in clinical
diabetes research, and then reviews how those methods have been
used to carry out cutting-edge studies of carbohydrate, lipid, and
protein metabolism in the disease.
These comprehensive yet concise collections of articles by world
experts survey the latest findings on the molecular biology of
diabetes and insulin action and synthesize a coherent understanding
of the subject. Topics include the etiology of type I and type II
diabetes, molecular and cellular aspects of insulin action, and the
mechanism of the insulin-stimulated glucose uptake.
This is a unique book on thyroid neoplasms in that it covers many
current topics in the area including tumor development, tumor
markers and preclinical treatment for advanced cancer as well as
practical approaches (radioiodine, ultrasound, thyroglobulin
monitoring and PET scanning). This book will give the general
reader and specialist a good foundation for what is currently going
on in the area of thyroid neoplasms.
*A translational approach to thyriod neoplasms
*Contributions from national experts in research and clinical
medicine
*Current and practical approaches to patients with thyroid
neoplasms
The discipline of Endocrinology encompasses diabetes and obesity,
two of the most common and pressing health care concerns today. The
Oxford American Handbook of Endocrinology & Diabetes concisely
reviews the entire discipline, providing a wealth of daily help for
students and residents managing patients with diabetes and obesity
as well as reproductive and neuroendocrine disorders, pediatric
endocrinology, and problems of the thyroid, pituitary, and adrenal
glands. Key topics such as genetics, therapeutic agents, and
results of major clinical trials are included, all in a compact and
easily-navigable package.
Being overweight dramatically increases the risk of diabetes.
Research shows that only a permanent lifestyle change can take
weight off and keep it off, and thus prevent diabetes in those who
might otherwise suffer from this debilitating and dreaded disease.
Living with Diabetes: Dr. Draznin's Plan for Better Health offers a
truly practical, and proven, approach to lifestyle change that will
stay with you long term: a simple way to lose weight and keep it
off, and to prevent or manage diabetes. Filled with amusing
anecdotes and down-to-earth advice that make the book both fun to
read and easy to follow, Living with Diabetes offers a dramatically
different method of weight loss and management based on the
refreshingly simple concepts of the Draznin Mile and the Draznin
Calorie, two unique strategies that can help you lose weight
quickly and safely. For this fully revised and updated edition, Dr.
Draznin has incorporated many recent research findings in nutrition
and weight managementadvances in our understanding of weight
regulation, energy expenditure, and how Americans can learn to
change the way they eat. An evaluation of fad diets such as South
Beach, Atkins, and the Zone has been added, while statistics on
obesity and health have been fully updated. Dr. Draznin also weighs
the risks and benefits of surgical approaches such as gastric
bypass, and discusses the newest methods of treating diabetes and
pre-diabetes. Drawing on his successful treatment of thousands of
overweight and diabetic patients over 30 years of medical practice,
Dr. Boris Draznin offers a practical and easy-to-follow plan that
will appeal to those who have or are at risk for diabetes, as well
as anyone interested in losing weight in a healthy and sustainable
manner.
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