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Patients don't present with a disease; they present with symptoms.
Using a practical, symptom-based organization, Nelson Pediatric
Symptom-Based Diagnosis: Common Diseases and their Mimics, 2nd
Edition, offers authoritative guidance on differential diagnosis
and treatment of diseases and disorders in children and
adolescents, and covers the symptoms you're likely to see in
practice, their mimics, and uncommon disorders. Drs. Robert M.
Kliegman, Heather Toth, Brett J. Bordini, and Donald Basel walk you
through what to consider and how to proceed when faced with common
symptoms such as cough, fever, headache, autistic-like behaviors,
chronic pain, chest pain, gait disturbances, and much more. Begins
with a presenting symptom and leads you through differential
diagnosis and a concise review of treatment recommendations.
Contains more than a dozen new topics including Disease Mimics: An
Approach to Undiagnosed Diseases, Autistic-like Behaviors, Shock,
Hypertension, Neurocognitive and Developmental Regression, Chronic
Pain, Hypertonicity, Movement Disorders, Hypermobility, and more.
Features a new focus on symptoms of rarer diseases that are mimics
of more common diseases. Offers a user-friendly approach to Altered
Mental Status such as coma and other CNS disorders, with numerous
clinically useful tables and figures to guide clinical decision
making in various care settings. Uses a highly templated format for
easy reference and quick answers to clinical questions, with the
same consistent presentation in each chapter: History, Physical
Examination, Diagnosis (including laboratory tests), Imaging,
Diagnosis, and Treatment. Includes numerous full-color
illustrations, algorithms, tables, and "red flags" to aid
differential diagnosis. Serves as an ideal companion to Nelson
Textbook of Pediatrics, 21st Edition. Content in this book is
referenced and linked electronically to the larger text, providing
easy access to full background and evidence-based treatment and
management content when you own both references. Enhanced eBook
version included with purchase. Your enhanced eBook allows you to
access all of the text, figures, and references from the book on a
variety of devices.
In this issue of Critical Care Clinics, guest editors Drs. Robert
M. Kliegman and Brett J. Bordini bring their considerable expertise
to the topic of Undiagnosed and Rare Diseases in Critical Care. Top
experts in the field cover key topics such as critical genetic
arrhythmia disorders, uncommon causes of rhabdomyolysis, status
epilepsy syndromes, autoimmune encephalitis, rapid-onset paralysis
and weakness, and more. Contains 17 relevant, practice-oriented
topics including understanding cognitive diagnostic errors in the
ICU; rapid WES/WGS in the ICU; diagnostic time-outs to improve
diagnosis; when "sepsis" is not sepsis: MAS, HLH, malignancies and
other sepsis mimics; all that wheezes is not asthma or
bronchiolitis; and more. Provides in-depth clinical reviews on
undiagnosed and rare diseases in critical care, offering actionable
insights for clinical practice. Presents the latest information on
this timely, focused topic under the leadership of experienced
editors in the field. Authors synthesize and distill the latest
research and practice guidelines to create clinically significant,
topic-based reviews.
Dr. Kliegman and Dr. Bordini have written a primer on Undiagnosed
and Rare Diseases in Children. Leading experts have presented the
current knowledge in the following areas: How Doctor's Think:
Common Diagnostic Errors in Clinical Judgment; Team-Based Approach
to Undiagnosed and Rare Diseases; Ending a Diagnostic Odyssey:
Family Education Counselling and Their Response to Eventual
Diagnosis; Eczema and Urticaria as Manifestations of Undiagnosed
and Rare Diseases; Usual and Unusual Manifestations of Familial
Hemophagocytic and Langerhans Cell Histiocytosis Syndromes; When
Autistic Behavior Suggests a Disease Other than Classic Autism;
Non-classic Inflammatory Bowel Disease in Young Infants; IPEX and
Other Disorders; Usual and Unusual Presentation of Mitochondrial
Disorders; When to Suspect Auto-inflammatory/Recurrent Fever
Syndromes; Primary and Secondary Causes of Autonomic Dysfunction;
Usual and Unusual Manifestations of Systemic and CNS Vasculitis;
Fever of Unknown Origin; Differentiating Familial Neuropathies from
Guillain-Barre Syndrome; and Munchausen by Proxy: A Factitious
Undiagnosed Disease. Readers will come away with cutting-edge
information to use immediately in their clinical management of
patients.
In collaboration with Consulting Editor, Dr. Lucky Jain, Drs.
Robert Kliegman and Bret Bordini have put together topics that
provide a current clinical update on the treatment and management
of undiagnosed and rare diseases in the neonate. Expert authors
have contributed clinical review articles on the following topics:
Neonatal Liver Failure; Neonatal Autoinflammatory Disorders; Rare
or Unusual Dermatologic Disorders In Neonates; Neonatal Immune
Deficiency; Congenital Diarrhea Syndromes; Nonimmune Hydrops; DNA
Depletion Syndromes; Genomic Approach to Dysmorphology Syndromes;
Nonimmune Anemias; Severe Metabolic Crisis (Metabolic Acidosis,
Unresponsive Hypoglycemia, Hyperammonemia); Heterotaxia Syndromes;
Neonatal Appendicitis; Avoiding Diagnostic Errors in Neonatology;
and Differentiating Congenital Myopathy from Congenital Muscular
Dystrophy. Readers will come away with the information they need to
improve outcomes in the neonate.
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