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Vector-borne diseases have increasingly emerged as significant
causes of human illnesses worldwide, largely due to environmental
changes (deforestation), population movements (migration and
travelling), international trades, and buildup of drug resistance.
These are presenting major challenge to the efficacy and use of
conventional tools for controlling vector-borne diseases.
Therefore, use of microbial approach for the control of
vector-borne diseases is gaining importance. This book
comprehensively reviews vector-borne diseases and their microbial
control, emphasizing majorly on ecofriendly ways of microbial
control.
This book comprehensively covers the latest development in
developing and deploying the genetically modified vectors,
particularly Anopheles and Aedes mosquitoes responsible for
transmitting malaria parasites and dengue viruses, the most deadly
and/or debilitating among all the vector-borne diseases. It is
considered timely and commensurate to bring about a book dealing
with the various ecological, biological and social as well as
regulatory aspects for the deployment of genetically modified
vectors in special context with the biosafety of humans, his
associates, and the environment. Written by an array of specialists
and experts in various subjects of genetically modified organisms,
this book centrally addresses the (i) basic principles of the
genetic manipulation of vectors and they are potential impact on
human and the environment, (ii) ecological, biological, ethical,
legal and social implications of the use of genetically modified
vectors, (iii) identification of potential hazards; assessment and
management of risks for human and environment; risk/benefit
analysis, (iv) principles and practices for the assessment and
management of biosecurity and biosafety in laboratories (and in the
field), (v) guiding principles for creation and management of
institutional or national biosafety review boards and ethics review
committees, and (vi) development and application of a biosafety
regulatory framework and its related legal principles at national
levels for securing the development and use of vector control
methods based on genetic modification strategies. This publication
will be useful to researchers, scientists, and professionals
engaged in academic and research institutions, government or
non-government, as well as students in universities and medical
colleges.
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