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Here in a single source is a complete spectrum of ideas on the
development of new anticancer drugs. Containing concise reviews of
multidisciplinary fields of research, this book offers a wealth of
ideas on current and future molecular targets for drug design,
including signal transduction, the cell division cycle, and
programmed cell death. Detailed descriptions of sources for new
drugs and methods for testing and clinical trial design are also
provided.
KEY FEATURES:
* One work that can be consulted for all aspects of anticancer drug
development
* Concise reviews of research fields, combined with practical
scientific detail, written by internationally respected
experts
* A wealth of ideas on current and future molecular targets for
drug design, including signal transduction, the cell division
cycle, and programmed cell death
* Detailed descriptions of the sources of new anticancer drugs,
including combinatorial chemistry, phage display, and natural
products
* Discussion of how new drugs can be tested in preclinical systems,
including the latest technology of robotic assay systems, cell
culture, and experimental animal techniques
* Hundreds of references that allow the reader to access relevant
scientific and medical literature
* Clear illustrations, some in color, that provide both
understanding of the field and material for teaching
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