Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers. Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.

Bruce Carlson's Human Embryology and Developmental Biology is one of the most detailed texts available for those who want to truly understand both the morphological and molecular aspects of human embryological development. Fully updated in its seventh edition, the book provides a thorough grounding in all aspects of embryology. It presents in detail the molecular and cellular basis for embryological processes, from early development through to development of body systems. It covers examples of congenital malformations and their underlying mechanisms, and comes complete with clinical vignettes and review questions to support learning. This book will suit medical and science students taking embryology courses as well as scientists and clinicians who find themselves returning to this topic throughout their careers. Clear and consistent writing style - highly readable and well-focused Extensively illustrated to demystify complex topics Good selection of original photographs of congenital anomalies to assist with identification Review questions and suggested readings for further learning Series of animations of complex embryological processes to accompany the text explanations Clinical correlation boxes, vignettes and summary boxes for quick revision An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud Many new drawings and photographs Thoroughly updated with recent research to advance understanding Expanded treatment of newly understood molecular pathways. Major updates on gametes, body axis formation, placental pathology, adipose tissue, intestinal and facial development

The fields of stem cell research, regenerative medicine, tissue engineering, and cloning are very closely related. It is important for researchers in each of these disciplines to be aware of the methods and principles in the others. Elsevier publishes some of the highest individual references in these areas. Bringing together the principles, applications, and basic understanding in these related areas of science will provide a new reference which is serve the needs of a variety of researchers. Edited by Dr. Bruce Carlson, "Stem CellAnthology" will be valuable to researchers and students who need to save time and link concepts to principles, applications, and methods in order to work more effectively and see links for potential collaborations.

Includes acollection of chapters by leaders in the stem cell field including the first researchers to discover iPS cells and multiple Nobel Laureates

Provides the most detailed introduction tobasic properties of major embryonic and adult stem cellsby highlightingbreakthrough discoveries inthe nervous system, spinal cord, heart, pancreas, epidermis, musculo-skeletal, retina - leading areas of stem cell research in human application

Detailstechnical laboratory set upfor practitioners, technicians, and administrators"

With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers.
* Creates a general understanding of one of the most fascinating and complex phenomena in biology
* Discusses the ability and diversity of regeneration in various organisms
* Explains the history and origins of cells in regenerating systems
* Includes information on stem cells and its important role in regeneration

Nueva edici?n de la obra de referencia en la disciplina que recoge toda la informaci?n necesaria para entender el desarrollo del embri?n humano, desde la concepci?n hasta el momento del nacimiento, con un enfoque claramente molecular. No obstante y a pesar de que se reflejan las ?ltimas investigaciones en regulaci?n g?nica, se?ales de transducci?n, receptores., la obra no pretende ser un tratado enciclop?dico. Cuando se hace referencia al nivel molecular no se hace en profundidad, ya que s?lo en una ocasi?n (cap. 4 y a modo de ejemplo) se reproducen todos los pasos de las v?as y las interacciones moleculares implicadas. Cuando se hace referencia a las correlaciones cl?nicas, el texto se organiza en forma de cuadro de texto y se utiliza siempre el mismo color (morado).Esta nueva edici?n presenta interesantes fotograf?as cl?nicas y dibujos muy claros que ayudan a memorizar de forma bastante f?cil los conceptos pertenecientes tanto a un proceso de desarrollo normal como anormal. Como importante novedad, esta edici?n presenta un enfoque molecular mucho m's profundo y facilita la comprensi?n e interpretaci?n de todos los pasos del desarrollo embrionario a trav's de im?genes 3D. Al final de cada uno de los cap?tulos, se incluyen preguntas de autoevaluaci?n para poder contrastar los conocimientos adquiridos.Otro recurso did?ctico que presenta la obra es la inclusi?n al final de cada cap?tulo de un resumen estructurado en puntos y de preguntas de repaso. Igualmente, a lo largo del texto aparecen las llamadas 'Vi?etas cl?nicas', que plantean un caso cuya respuesta se encuentra al final del libro junto con las de repaso. Se incluye tambi?n el recurso "online" "Student Consult" que cuenta con animaciones, aparte de todo el contenido extra que ofrece este recurso.