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Based on presentations by world-renowned investigators at the 72nd
annual Cold Spring Harbor Symposium on Quantitative Biology, this
volume reviews the latest advances in biological clocks and
rhythms. Topics include genetic and cellular studies aimed at
characterizing circadian mechanisms; systems approaches to
understanding physiological, endocrine, and neural networks; and
models used for studying mental and physical cycles. A variety of
normal and abnormal chronobiological patterns are discussed,
including sleep, aging, migration, hibernation, seasonality,
depression, and arrhythmias.
Based on presentations by world-renowned investigators at the 73rd
annual Cold Spring Harbor Symposium on Quantitative Biology, this
volume reviews the latest advances in research on the control and
regulation of stem cells. The topics covered include nuclear
reprogramming, regulation of stem cell self-renewal and
differentiation, the stem cell niche, and signaling and gene
regulation in stem cells. Studies of embryonic stem cells and adult
stem cells are covered, along with research shedding light on the
roles of these cells in regeneration and cancer.
This volume is based on presentations by the world-renowned
investigators who gathered at the 74th annual Cold Spring Harbor
Symposium on Quantitative Biology to celebrate the 150th
anniversary of the publication of Charles Darwin's On the Origin of
Species. It reviews the latest advances in research into evolution,
focusing on the molecular bases for evolutionary change. The topics
covered include the appearance of the first genetic material, the
origins of cellular life, evolution and development, selection and
adaptation, and genome evolution. Human origins, cognition, and
cultural evolution are also covered, along with social
interactions. The line-up of speakers comprised a stellar list of
preeminent scientists and thinkers such as the zoologist and
prolific author E. O. Wilson (Harvard University); Jack W. Szostak
(Harvard Medical School), a 2009 Nobel Prize winner who studies the
chemistry of life's origins; and Nobel Prize winner and former
president of HHMI Thomas Cech (Colorado Institute for Molecular
Biotechnology), to name just a few.
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