This volume addresses the history and epistemology of early modern cosmology. The authors reconstruct the development of cosmological ideas in the age of 'scientific revolution' from Copernicus to Leibniz, taking into account the growth of a unified celestial-and-terrestrial mechanics. The volume investigates how, in the rise of the new science, cosmology displayed deep and multifaceted interrelations between scientific notions (stemming from mechanics, mathematics, geometry, astronomy) and philosophical concepts. These were employed to frame a general picture of the universe, as well as to criticize and interpret scientific notions and observational data. This interdisciplinary work reconstructs a conceptual web pervaded by various intellectual attitudes and drives. It presents an historical-epistemological unified itinerary which includes Copernicus, Kepler, Galileo, Descartes, Huygens, Newton and Leibniz. For each of the scientists and philosophers, a presentation and commentary is made of their cosmological views, and where relevant, outlines of their most relevant physical concepts are given. Furthermore, the authors highlight the philosophical and epistemological implications of their scientific works. This work is helpful both as a synthetic overview of early modern cosmology, and an analytical exposition of the elements that were intertwined in early-modern cosmology. This book addresses historians, philosophers, and scientists and can also be used as a research source book by post-graduate students in epistemology, history of science and history of philosophy.