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Moyamoya disease (MMD) was first reported as a new entity among
vascular disorders in 1957. Named for the abnormal vascular
networks found around the occluded distal internal carotid artery,
it is the most common pediatric cerebrovascular disease in East
Asia. In recent years large amounts of data on MMD have been
collected and important investigations have been carried out in
Japan and Korea, even as the pathophysiology of the disease remains
to be discovered. This monograph covers a diversity of topics and
presents a systematic compilation of the data and current status of
MMD in clinical practice and basic research. With contributions by
more than 70 authors, the book includes sections on genetics,
computational analysis of hemodynamic shear stress, new imaging
techniques, and endovascular treatment of MMD, along with practical
applications and future directions for gene and stem cell
therapies. For neurosurgeons as well as neurologists and
pediatricians, this volume will help lead to more efficient and
informed management of MMD.
Moyamoya disease (MMD) was first reported as a new entity among
vascular disorders in 1957. Named for the abnormal vascular
networks found around the occluded distal internal carotid artery,
it is the most common pediatric cerebrovascular disease in East
Asia. In recent years large amounts of data on MMD have been
collected and important investigations have been carried out in
Japan and Korea, even as the pathophysiology of the disease remains
to be discovered. This monograph covers a diversity of topics and
presents a systematic compilation of the data and current status of
MMD in clinical practice and basic research. With contributions by
more than 70 authors, the book includes sections on genetics,
computational analysis of hemodynamic shear stress, new imaging
techniques, and endovascular treatment of MMD, along with practical
applications and future directions for gene and stem cell
therapies. For neurosurgeons as well as neurologists and
pediatricians, this volume will help lead to more efficient and
informed management of MMD.
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