This new edition of our bestselling book, Lu s Basic Toxicology, provides a number of key benefits that make it a must-read for toxicology specialists worldwide, including: Revision of a Bestseller - the new Sixth Edition provides the critical updates toxicologists need to keep up with the changing times New Information - on over-the-counter preparations, lactation, and occupational toxicology, providing clarity and insight into a rapidly evolving subject Comprehensive - Updated, topical additions - new chapters on Nanotoxicology and Toxicity of Endocrine System provide you with information not currently available elsewhere Expert Editors - Kacew and Lee offers a distillation of decades and research and teaching experience in toxicology, providing authoritative guidance for both students and practicing professionals Practical- Easy to read information at your fingertips - In-depth, yet concise presentation of material split into four key sections that include separate subject and chemical indexes all while in the 6 x 9 format makes this a useful, quick pocket-guide for the more experienced researcher.

Continuing a long tradition, Lu's Basic Toxicology, Seventh Edition, combines relatively comprehensive coverage of toxic substances in food, air, and water with brevity, thereby continuing to serve as an updated introductory text for toxicology students and for those involved in allied sciences that require a background in toxicology. The new edition, which now becomes an edited work with contributions from experts around the globe, features four new chapters and a number of existing chapters that have been updated and expanded, notably those on mechanisms of toxic effects, conventional toxicity studies, the cardiovascular system, and risk assessment and regulatory toxicology. The book consists of four parts (Part I-Part IV) that provide guidance on principles of toxicology and testing procedures for toxicities as well as a concise, yet detailed, mechanism of both target organ and nontarget organ toxicities. The book is rounded off with a final section (Part IV) on the toxic effects of chemicals and risk assessment, giving toxicologists, both students and practicing professionals, the necessary tools to enhance their practice. This edition includes new chapters on Clinical Toxicology, Systems Toxicology, Chemicals and Children, and Toxicology of Reproductive Systems, providing the essentials of these topics in the same style as the other chapters in the book. With separate subject and chemical indexes, this is a useful, quick shelf reference for everyone working in toxicology today.

Continuing a long tradition, Lu’s Basic Toxicology, Seventh Edition, combines relatively comprehensive coverage of toxic substances in food, air, and water with brevity, thereby continuing to serve as an updated introductory text for toxicology students and for those involved in allied sciences that require a background in toxicology. The new edition, which now becomes an edited work with contributions from experts around the globe, features four new chapters and a number of existing chapters that have been updated and expanded, notably those on mechanisms of toxic effects, conventional toxicity studies, the cardiovascular system, and risk assessment and regulatory toxicology.

The book consists of four parts (Part I–Part IV) that provide guidance on principles of toxicology and testing procedures for toxicities as well as a concise, yet detailed, mechanism of both target organ and nontarget organ toxicities. The book is rounded off with a final section (Part IV) on the toxic effects of chemicals and risk assessment, giving toxicologists, both students and practicing professionals, the necessary tools to enhance their practice. This edition includes new chapters on Clinical Toxicology, Systems Toxicology, Chemicals and Children, and Toxicology of Reproductive Systems, providing the essentials of these topics in the same style as the other chapters in the book. With separate subject and chemical indexes, this is a useful, quick shelf reference for everyone working in toxicology today.

Table of Contents

PART I: General Principles of Toxicology. History of Toxicology. Absorption, Distribution, and Excretion of Toxicants. Metabolism of Toxicants. Toxic Effects (Mechanisms of Toxic Effects). Modifying Factors of Toxic Effects. Conventional Toxicity Studies. Systems Toxicology. PART II: Testing Procedures for Nontarget Organ Toxicities. Carcinogenesis. Mutagenesis. Developmental Toxicology. Lactation. PART III: Target Organs and Systems. Toxicology of the Liver. Toxicology of the Kidney. Toxicology of the Immune System. Respiratory System Inhalation Toxicology. Toxicology of the Skin. Toxicology of the Eye. Toxicology of the Nervous System. Cardiovascular System. Toxicology of Reproductive Systems. Toxicology of the Endocrine System. PART IV: Toxic Substances and Risk Assessment. Food Additives and Contaminants. Toxicity of Pesticides. Nanotoxicology. Toxicity of Metals. Environmental Pollutants. Occupational Toxicology. Chemicals and Children. Clinical Toxicology. Risk Assessment and Regulatory Toxicology.