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Assembling a program in bioinorganic chemistry that is scientifi
cally relevant, well defined, and self-consistent is not an easy
task. In this attempt we decided to consider zinc enzymes, copper
oxidases, cytochromes and cytochrome oxidase. The choice is in part
due to the great attention that the current specialized literature
devotes to these topics, which are now debated among chemists,
biochemists, biophysicists, etc .. We believe that hydration
reactions, hydrolytic and oxidative processes have much in common
from the point of view of the reaction mechanisms, the
comprehension of which represents a frontier of science. For these
reasons these topics have been the subject of the NATO-ASI held at
San Miniato, Pisa, Italy, from May 28 to June 8, 1982. We hope we
can transfer here the main conclusions of what (we believe) was a
very stimulating scientific meeting. We would like to thank the
local saving bank, Cassa di Risparmio di San Miniato, for helping
in many ways. The financial contribution from the European Research
Office of the US Army, and from the Bruker Spectrospin s.r.l.,
Italy, is also acknowledged. The National Science Foundation of the
United States has provided a travel grant to one of the
participants from the U.S.A. We are grateful to the NATO Scientific
Affairs Division which provided a grant to finance this Institute."
Assembling a program in bioinorganic chemistry that is scientifi
cally relevant, well defined, and self-consistent is not an easy
task. In this attempt we decided to consider zinc enzymes, copper
oxidases, cytochromes and cytochrome oxidase. The choice is in part
due to the great attention that the current specialized literature
devotes to these topics, which are now debated among chemists,
biochemists, biophysicists, etc .. We believe that hydration
reactions, hydrolytic and oxidative processes have much in common
from the point of view of the reaction mechanisms, the
comprehension of which represents a frontier of science. For these
reasons these topics have been the subject of the NATO-ASI held at
San Miniato, Pisa, Italy, from May 28 to June 8, 1982. We hope we
can transfer here the main conclusions of what (we believe) was a
very stimulating scientific meeting. We would like to thank the
local saving bank, Cassa di Risparmio di San Miniato, for helping
in many ways. The financial contribution from the European Research
Office of the US Army, and from the Bruker Spectrospin s.r.l.,
Italy, is also acknowledged. The National Science Foundation of the
United States has provided a travel grant to one of the
participants from the U.S.A. We are grateful to the NATO Scientific
Affairs Division which provided a grant to finance this Institute."
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