This new book is a personal reminiscence by retired railwayman John C Morgan, who has put together the very best of his own collection of stunning colour photographs to portray the life and times of the Southern Railway. At a time when the railway scene was changing forever, John was out and about around the network capturing all those changes on film - whether it is steam, diesel or electric, the result is a veritable feast of colour railway nostalgia

Arising from the third Cary Conference held in 1989, Comparative Analyses of Ecosystems investigates the utility and limitations of cross-system comparisons in ecology. The contributors, all well-known in their field, support their conclusions on the use and meaning of such comparisons by presenting novel analyses of data utilizing a variety of cross-system approaches in marine, freshwater, and terrestrial systems.

KENNETH A. FOON and ALTON C. MORGAN, JR. Passive immunotherapy using heteroantisera for the treatment of cancer in animals and humans has been studied for over 50 years. Attempts have been made to treat animal tumors with sera from immunized syngeneic, allogeneic, or xenogeneic animals. A number of studies of passive immunotherapy using heterologous antisera in humans have also been performed. These studies have generally been attempted in patients with large tumor burdens, and as would be expected, results have been transient at best. A wide variety of solid tumors as well as leukemias and lym- phomas have been treated with antisera raised in sheep, horses, rabbits, and goats. Problems such as anaphylaxis, serum sick- ness, and severe cytopenias have been encountered with these antisera. There are a number of potential mechanisms by which unconju- gated antibodies might be cytotoxic to tumor cells. Antibodies bound to the cell surface membrane of tumor cells may lead to cell lysis by complement-dependent or antibody-dependent cellu- lar cytotoxicity. Circulating tumor cells bound by antibody may be more susceptible to phagocytosis by the reticuloendothelial system. Antibody bound to the cell surface membrane of tumor cells may enhance immunogenicity of the tumor cell leading to activation of the host's immune system.

In this book the authors have applied research knowledge to the solution of practical problems facing wildlife conservation in freshwater habitats. Subjects covered include: evaluation of the conservation interest of sites; practical protection and management of freshwater habitats; species conservation.

The forces of globalization are shifting our world, including the public sector, away from hierarchy and command and control toward one of collaboration and networks. The way public leadership is thought about and practiced must be, and is being, transformed. This volume in the "Transformational Trends in Governance & Democracy" series explores what the shift looks like and also offers guidance on what it should look like. Specifically, the book focuses on the role of "career leaders" - those in public service - who are agents of change not only in their own organizations, but also in their communities and policy domains. These leaders work in network settings, making connections and collaborating to create public value and advance the common good. Featuring the insights of an authoritative group of contributors, the volume offers a mix of scholarship, from philosophical discussions to conceptual models to empirical studies that, taken together, will help inform the transformation of public leadership that is already underway.

The forces of globalization are shifting our world, including the public sector, away from hierarchy and command and control toward one of collaboration and networks. The way public leadership is thought about and practiced must be, and is being, transformed. This volume in the "Transformational Trends in Governance & Democracy" series explores what the shift looks like and also offers guidance on what it should look like. Specifically, the book focuses on the role of "career leaders" - those in public service - who are agents of change not only in their own organizations, but also in their communities and policy domains. These leaders work in network settings, making connections and collaborating to create public value and advance the common good. Featuring the insights of an authoritative group of contributors, the volume offers a mix of scholarship, from philosophical discussions to conceptual models to empirical studies that, taken together, will help inform the transformation of public leadership that is already underway.

Art criticism in the 1980s was highly influenced by market forces that somewhat changed the face of the art world. A mediocre show purchased by a wealthy investor or collector received disproportionate coverage in the New York press, particularly those glossy, four-color journals that were highly dependent upon the advertising dollars of galleries, auction houses, vodka companies, airlines and fashion designers. Lost in the coverage of market-driven art was that it was not necessarily the most advanced or even the most significant work of the decade. This work provides an alternative viewpoint to the general American cultural discourse of the 1980s, showing that the real situation was not the exclusionary rhetoric of Postmodernism but was instead the conflict between late Modernism and Conceptual Art. The 24 essays range from discussions on Joseph Beuys and Allan Kaprow to studies of French artist Tania Mouraud and Polish artist Jan Zakrzewski. It also includes a lengthy commentary on art and technology, along with a look at performance and installation art.

In this book the authors have applied research knowledge to the solution of practical problems facing wildlife conservation in freshwater habitats. Subjects covered include: evaluation of the conservation interest of sites; practical protection and management of freshwater habitats; species conservation.

KENNETH A. FOON and ALTON C. MORGAN, JR. Passive immunotherapy using heteroantisera for the treatment of cancer in animals and humans has been studied for over 50 years. Attempts have been made to treat animal tumors with sera from immunized syngeneic, allogeneic, or xenogeneic animals. A number of studies of passive immunotherapy using heterologous antisera in humans have also been performed. These studies have generally been attempted in patients with large tumor burdens, and as would be expected, results have been transient at best. A wide variety of solid tumors as well as leukemias and lym- phomas have been treated with antisera raised in sheep, horses, rabbits, and goats. Problems such as anaphylaxis, serum sick- ness, and severe cytopenias have been encountered with these antisera. There are a number of potential mechanisms by which unconju- gated antibodies might be cytotoxic to tumor cells. Antibodies bound to the cell surface membrane of tumor cells may lead to cell lysis by complement-dependent or antibody-dependent cellu- lar cytotoxicity. Circulating tumor cells bound by antibody may be more susceptible to phagocytosis by the reticuloendothelial system. Antibody bound to the cell surface membrane of tumor cells may enhance immunogenicity of the tumor cell leading to activation of the host's immune system.

Arising from the third Cary Conference held in 1989, Comparative Analyses of Ecosystems investigates the utility and limitations of cross-system comparisons in ecology. The contributors, all well-known in their field, support their conclusions on the use and meaning of such comparisons by presenting novel analyses of data utilizing a variety of cross-system approaches in marine, freshwater, and terrestrial systems.

When origami met the worlds of design and engineering, both fields embraced the ancient art form, using its principles and practices to discover new problems and to generate inventive solutions. This book demonstrates the potential of folding to improve the way things work, simplify how products are produced, and make possible new objects otherwise impossible. The solar collector, the felt stool, and the surgery tool have all been influenced in some way by folding paper. The example section is organized to show the folded figure next to the product prototype that was inspired by that work of origami. We have included models made from an array of materials over a range of sizes. This includes everything from a microscopic mechanism to huge solar panels designed to unfold in outer space. Most entries are at the prototype phase-meaning that physical hardware has been built to demonstrate the concept, but that the examples are not necessarily available commercially. Y Origami? also includes brief learning activities related to paper folding, such as a discussion of Euler's formula, angular measurements, and developable surfaces, along with more advanced topics. Throughout the book many diagrams and photographs illustrate the advancing concepts and methods of origami as an art form and a problem-solving strategy.

Kidney transplantation is a medical procedure performed on patients with end-stage kidney disease that can increase their life expectancy by several years. However, the procedure involves some risk and potential complications. Chapter One of this monograph summarizes the current strategy for diagnosis and treatment of chronic kidney disease-associated mineral bone disease (CKD-MBD) in kidney transplant recipients and aims to demonstrate the latest findings and therapeutic options in the field beyond recent published guidelines. Chapter Two describes the necessity of involving a psychiatrist in the transplant team to facilitate positive outcomes in kidney transplants, as psychological factors can contribute to treatment non-compliance and other issues. Chapter Three defines the surgical techniques used in living donor nephrectomy, discusses the use and reliability of these techniques in different patient groups, and examines the long-term follow-up results of donors and recipients. Lastly, Chapter Four discusses the variables involved in treating patients with autosomal dominant polycystic kidney disease (ADPCKD), whose enlarged and deformed kidneys can complicate kidney transplantation.