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Effective new treatments of heart disease are based on a refined
understanding of cellular function and the heart's response to
environmental stresses. Not surprisingly therefore, the field of
experimental cardiology has experienced a phase of rapid expo
nential growth during the last decade. The acquisition of new
knowledge has been so fast that textbooks of cardiology or
textbooks of cardiovascular physiology are often hard-pressed to
keep up with the most important conceptual advances. Witness the
explosive increase in knowledge about signaling pathways of cardiac
growth, transcrip tional regulation of cardiac metabolism, hormonal
signaling, and the complex responses of the heart to ischemia,
reperfusion, or ischemic preconditioning. This book is meant to
bridge the gap between original literature and textbook reviews. It
brings together inves tigators of various backgrounds who share
their expertise in the biology of myocardial ischemia. Each chapter
is a self-contained mini-review, but it will soon become apparent
to the reader that there is also a common thread: Molecular and
cellular cardiology has never been more exciting than now, but ever
more exciting times are yet to come. The Editors ACKNOWLEDGEMENTS -
Publication of this book was generously supported by Sanofi-Aventis
Hellas. - Eikon creative team provided the technical assistance in
preparing the manuscripts. - We thank Dr. Bernard Swynghedauw for
all his scientific support.
Effective new treatments of heart disease are based on a refined
understanding of cellular function and the heart's response to
environmental stresses. Not surprisingly therefore, the field of
experimental cardiology has experienced a phase of rapid expo
nential growth during the last decade. The acquisition of new
knowledge has been so fast that textbooks of cardiology or
textbooks of cardiovascular physiology are often hard-pressed to
keep up with the most important conceptual advances. Witness the
explosive increase in knowledge about signaling pathways of cardiac
growth, transcrip tional regulation of cardiac metabolism, hormonal
signaling, and the complex responses of the heart to ischemia,
reperfusion, or ischemic preconditioning. This book is meant to
bridge the gap between original literature and textbook reviews. It
brings together inves tigators of various backgrounds who share
their expertise in the biology of myocardial ischemia. Each chapter
is a self-contained mini-review, but it will soon become apparent
to the reader that there is also a common thread: Molecular and
cellular cardiology has never been more exciting than now, but ever
more exciting times are yet to come. The Editors ACKNOWLEDGEMENTS -
Publication of this book was generously supported by Sanofi-Aventis
Hellas. - Eikon creative team provided the technical assistance in
preparing the manuscripts. - We thank Dr. Bernard Swynghedauw for
all his scientific support.
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