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Leukocyte adhesion molecules have been the subject of intense basic
and preclinical research. Results from clinical trials obtained
sofar with antibodies directed towards these surface proteins offer
promise for the prevention of graft rejection and effective
treatment of acute and chronic inflammatory disease. This volume
presents a comprehensive review of contemporary research on the
structure, function and regulation of leukocyte adhesion molecules
and their ligands, from the molecular to the clinical level. The
blend of basic science and clinical applications presented in
Structure, Function and Regulation of Molecules Involved in
Leukocyte Adhesion provides clear evidence of the biological
importance of cell-cell interactions and the many potential
clinical dividends afforded by understanding the molecular basis of
cell adhesion. It will appeal to a broad range of readers in
immunology and cell biology.
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