The Selected Works of C. H. Waddington reissues seven titles from Waddington's impressive oeuvre. The titles in question cover a range of topics, from genetics and embryology to ethics in science and contemporary biological thought.

First published in 1935 (this edition in 1946), this short account of the science of embryology was the first book in English to provide a simple outline of the whole of this important subject. The study of development is perhaps the best method of approach to the most fundamental of all biological problems, the problem of how all the diverse activities are integrated so as to make up a complete individual organism. The book gives a short sketch of the general pattern on which all animals are built, but devotes more attention to the factors which cause the development of the elements in the pattern, and which then bring them into correct relations with one another. This volume is simply written in order to enable the general reader to understand the revolutionary advances made in the subject at that time.

First published in 1939 (second impression in 1950), this book provides an account of the changes in, and main principles of, genetics at that time. These are illustrated by references to the most authoritative and then recent investigations. Special attention is paid to the way in which genetics overlaps with other fields of inquiry, since it is often in these border-line subjects that the most important advances are to be expected. The book is particularly arranged to suit the convenience of students whose previous knowledge of genetics is small, and contains annotated bibliographies of suggestions for further reading.

First published in 1960, this book discusses the ethical implications of the view of man's nature and his place in the biological world. C. H. Waddington highlights issues of the time, such as social upheavals related to social mobility, and the changing nature of philosophical thinking in relation to the nature of good. The author argues that man differs from all other animals in his ability for social teaching and learning and that this provides him with a second method of evolutionary advance, in addition to biology. He advances this through the idea that man has the capacity to entertain ethical ideas, which is an essential and necessary feature of this new mode of evolution. From here he draws the conclusion that a consideration of the broad trends of evolution provides a framework within which we can rationally discuss the relative merits of the various systems of ethical belief current in the world. In presenting his argument, Waddington draws on research in biology, psychology, the social sciences, and philosophy. He concludes with a short consideration of some of the most important ethical problems facing mankind at the time of the book's publication.

First published in 1942 (second impression 1944), this book forms a debate about the endeavour to find an intellectual basis for ethics in science.

First published in 1961, this book explains the main trends and problems in modern biological thought, at that time. It was based on lectures presented at the University College of the West Indies, Jamaica, in 1960 to members from different faculties and is therefore an accessible guide for all to the subject.

This book explores the relationship between science, culture, and society. It discusses biological assumptions made by various communities on human beings and compares them with the scientific attitude. The book acts as a historical document, conveying some of the feeling of living through WWII.

At least until cloning becomes the order of the day, Rene Dubos contends that each human being is unique, unprecedented, unrepeatable. However, today each person faces the critical danger of losing this very humanness to his mechanized surroundings. Most people spend their days in a confusion of concrete and steel, trapped "in the midst of noise, dirt, ugliness and absurdity." So begins the essential message of the work of one of the great figures in microbiology and experimental pathology of this century.Is the human species becoming dehumanized by the condition of his environment? So Human an Animal is an attempt to address this broad concern, and explain why so little is being done to address this issue. The book sounds both an urgent warning, and offers important policy insights into how this trend towards dehumanization can be halted and finally reversed. Dubos asserts that we are as much the product of our total environment as of our genetic endowment. In fact, the environment we live in can greatly enhance, or severely Hmit, the development of human potential. Yet we are deplorably ignorant of the effects of our surroundings on human life. We create conditions which can only thwart human nature.So Human an Animal is a book with hope no less than alarm. As Joseph Wood Krutch noted at the time, Dubos shows convincingly "why science is indispensable, not omnipotent." Science'can change our suicidal course by learning to deal analytically with the living experience of human beings, by supplementing the knowledge of things and of the body machine with a science of human life. Only then can we give larger scope to human freedom by providing a rational basis for option and action. Timely, eloquent, and guided by a deep humanistic spirit, this new edition is graced by a succinct and careful outline of the life and work of the author.

First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate 'things' in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.

First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate 'things' in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.

Biological Processes in Living Systems is the fourth and final volume of the Toward a Theoretical Biology series. It contains essays that deal in detail with particular biological processes: morphogenesis of pattern, the development of neuronal networks, evolutionary processes, and others. The main thrust of this volume brings relevance to the general underlying nature of living systems.

Faced with trying to understand how the complexity of molecular microstates leads to the relative simplicity of phenome structures, Waddington--on behalf of his colleagues--stresses on the structure of language as a paradigm for a theory of general biology. This is language in an imperative mood: a set of symbols, organized by some form of generative grammar, making possible the conveyance of commands for action to produce effects on the surroundings of the emitting and the receiving entities. "Biology," he writes, "is concerned with algorithm and program."

Among the contributions in this volume are: "The Riemann-Hugoniot Catastrophe and van der Waals Equation," David H. Fowler; "Differential Equations for the Heartbeat and Nerve Impulse," E. Christopher Zeeman; "Structuralism and Biology," Rene Thom; "The Concept of Positional Information and Pattern Formation," Lewis Wolpert; "Pattern Formation in Fibroblast Cultures," Tom Elsdale; "Form and Information," C. H. Waddington; "Organizational Principles for Theoretical Neurophysiology," Michael A. Arbib; "Stochastic Models of Neuroelectric Activity," Jack D. Cowan. Biological Processes in Living Systems is a pioneering volume by recognized leaders in an ever-growing field.

At least until cloning becomes the order of the day, Rene Dubos contends that each human being is unique, unprecedented, unrepeatable. However, today each person faces the critical danger of losing this very humanness to his mechanized surroundings. Most people spend their days in a confusion of concrete and steel, trapped "in the midst of noise, dirt, ugliness and absurdity." So begins the essential message of the work of one of the great figures in microbiology and experimental pathology of this century.

Is the human species becoming dehumanized by the condition of his environment? So "Human an Animal "is an attempt to address this broad concern, and explain why so little is being done to address this issue. The book sounds both an urgent warning, and offers important policy insights into how this trend towards dehumanization can be halted and finally reversed. Dubos asserts that we are as much the product of our total environment as of our genetic endowment. In fact, the environment we live in can greatly enhance, or severely Hmit, the development of human potential. Yet we are deplorably ignorant of the effects of our surroundings on human life. We create conditions which can only thwart human nature.

So "Human an Animal "is a book with hope no less than alarm. As Joseph Wood Krutch noted at the time, Dubos shows convincingly "why science is indispensable, not omnipotent." Science'can change our suicidal course by learning to deal analytically with the living experience of human beings, by supplementing the knowledge of things and of the body machine with a science of human life. Only then can we give larger scope to human freedom by providing a rational basis for option and action. Timely, eloquent, and guided by a deep humanistic spirit, this new edition is graced by a succinct and careful outline of the life and work of the author.

This is the third, penultimate volume in the Toward a Theoretical Biology series. The contributors agree that there is a major problem in finding methods of dealing with the great complexity of biological systems. Molecular biology has given us considerable insight into the nature of the elementary units and processes of life, but to understand how these are put together to form systems that are usually too complicated to be analysed completely, but exhibit global properties of simplicity, presents biologists with an intellectual challenge that physical sciences and chemistry must also face. The problem is approached from several different angles: quantum physics, topology, and statistical mechanics. A stimulating discussion is recorded: that the behaviour of randomly constructed networks exhibits simplicity. Thoughtful analyses of complexities in such basic biological processes as the genetic control of differentiation, evolution, and ecology is also included. Some of the questions dealt with are: What kinds of theories should we wish to have in connection with developmental biology? And have we got them? The subject matter of 'Organization Stability and Process' is defined as the basic concept of biology. None of the contributors herein contained is a molecular biologist in the modern sense, but molecular biology casts a shadow over this work, at least in so far as they challenge its interpretative aggressiveness and its enthusiastic but unendearing self-confidence and self-sufficiency. This volume inaugurates a new and authentic style of scientific literature. The contributions are thoughtful, imaginative, illuminating, and exceptionally well written.

First published in 1961, this book explains the main trends and problems in modern biological thought, at that time. It was based on lectures presented at the University College of the West Indies, Jamaica, in 1960 to members from different faculties and is therefore an accessible guide for all to the subject.

First published in 1941 (this edition in 1968), this book explores the relationship between science, culture, and society- focusing on human beings, and human communities. Here, C. H. Waddington uses the concept of science to mean more than factual information about genes and haemoglobin and his subject is the effect of scientific ways of speaking on the ways in which people look at the world around them. The work discusses biological assumptions made by various communities, particularly fascist movements, on human beings and compares them with the scientific attitude. The Nazis for instance spoke about 'racial purity' and 'German blood' but these expressions, whilst arousing emotion, had, and have, no rational meaning- they are inaccurate and tell us nothing of human genetics. As well as presenting a scientific argument, being published initially in 1941, this book also acts as a historical document, conveying some of the feeling of living through WWII. It highlights the fact that science and scientific assumptions have very wide implications for the whole conduct of life.

First published in 1956, this book was considered the first comprehensive and unitary work on the subject since 1934. It provides an analysis of the relations between genetics and epigenetics, between genes and their effects. The book will be of interest to ebryologists, but also to more general biologists.

First published in 1960, this book discusses the ethical implications of the view of man's nature and his place in the biological world. C. H. Waddington highlights issues of the time, such as social upheavals related to social mobility, and the changing nature of philosophical thinking in relation to the nature of good. The author argues that man differs from all other animals in his ability for social teaching and learning and that this provides him with a second method of evolutionary advance, in addition to biology. He advances this through the idea that man has the capacity to entertain ethical ideas, which is an essential and necessary feature of this new mode of evolution. From here he draws the conclusion that a consideration of the broad trends of evolution provides a framework within which we can rationally discuss the relative merits of the various systems of ethical belief current in the world. In presenting his argument, Waddington draws on research in biology, psychology, the social sciences, and philosophy. He concludes with a short consideration of some of the most important ethical problems facing mankind at the time of the book's publication.

First published in 1942 (second impression 1944), this book forms a debate about the endeavour to find an intellectual basis for ethics in science.

First published in 1935 (this edition in 1946), this short account of the science of embryology was the first book in English to provide a simple outline of the whole of this important subject. The study of development is perhaps the best method of approach to the most fundamental of all biological problems, the problem of how all the diverse activities are integrated so as to make up a complete individual organism. The book gives a short sketch of the general pattern on which all animals are built, but devotes more attention to the factors which cause the development of the elements in the pattern, and which then bring them into correct relations with one another. This volume is simply written in order to enable the general reader to understand the revolutionary advances made in the subject at that time.

First published in 1939 (second impression in 1950), this book provides an account of the changes in, and main principles of, genetics at that time. These are illustrated by references to the most authoritative and then recent investigations. Special attention is paid to the way in which genetics overlaps with other fields of inquiry, since it is often in these border-line subjects that the most important advances are to be expected. The book is particularly arranged to suit the convenience of students whose previous knowledge of genetics is small, and contains annotated bibliographies of suggestions for further reading.

This is the third, penultimate volume in the Toward a Theoretical Biology series. The contributors agree that there is a major problem in finding methods of dealing with the great complexity of biological systems. Molecular biology has given us considerable insight into the nature of the elementary units and processes of life, but to understand how these are put together to form systems that are usually too complicated to be analysed completely, but exhibit global properties of simplicity, presents biologists with an intellectual challenge that physical sciences and chemistry must also face. The problem is approached from several different angles: quantum physics, topology, and statistical mechanics. A stimulating discussion is recorded: that the behaviour of randomly constructed networks exhibits simplicity. Thoughtful analyses of complexities in such basic biological processes as the genetic control of differentiation, evolution, and ecology is also included. Some of the questions dealt with are: What kinds of theories should we wish to have in connection with developmental biology? And have we got them? The subject matter of 'Organization Stability and Process' is defined as the basic concept of biology. None of the contributors herein contained is a molecular biologist in the modern sense, but molecular biology casts a shadow over this work, at least in so far as they challenge its interpretative aggressiveness and its enthusiastic but unendearing self-confidence and self-sufficiency. This volume inaugurates a new and authentic style of scientific literature. The contributions are thoughtful, imaginative, illuminating, and exceptionally well written.

First published in 1956, this book was considered the first comprehensive and unitary work on the subject since 1934. It provides an analysis of the relations between genetics and epigenetics, between genes and their effects. The book will be of interest to ebryologists, but also to more general biologists.

Originally published in 1952 as part of the Cambridge Biological Studies series, this book presents contemporary theories on embryology using the example of the bird embryo. Waddington reviews the modern experimental embryology of birds, and touches on topics such as plumage development and the developmental actions of mutant genes. This book will be of value to anyone with an interest in embryology or the history of epigenetics.