The verrucarins and roridins are secondary metabolites of the soil fungi Myrothecium verrucaria (Albertini et Schweinitz) Ditmar ex Fries and Myrothecium roridum Tode ex Fries. The species Myrothecium belongs to the fungi imperfecti, order of Moniliales, family Tubercularia- ceae (30, 17, 32). The distinction between these and other closely related fungal species is difficult. It has been studied and discussed by various authors (82, 16, 55, 75, 62, 43). Myrothecium species are parasitic on leaves of Gardenia, tomatoes, violets, kidney beans, snapdragons and other common plants. They are also found on decaying tissue and in soil. It was known earlier that cultures of the two species mentioned exhibit cellulolytic properties due to the presence of a very active cellulase which was used for the treatment of cellulose during the production of textiles [for leading references see (42, 66)]. The first investigation of the secondary metabolites of these micro- organisms was carried out by BRIAN and MCGOWAN (16). They isolated a crystalline compound, designated as glutinosin and assigned the formula C4sH60016, from cultures of Metarrhizium glutinosum S. Pope, which in fact is a Myrothecium species (82, 55). Glutinosin exhibited anti- fungal activity. Eight years later BOWDEN and SCHANTZ (14) described the isolation and characterization of a dermatitic or skinirritating crystal- line compound melting at 38 , and possessing the formula C H 04, 1s 22 from culture filtrates of Myrothecium verrucaria. They suspected the presence of additional biologically active substances.

'Wow!!! Wow!!!! Wow!!! This book is a total page turner and will keep you guessing with every page. Halfway through I thought I had it figured out and then BAM! The ending floored me' Michelle, NetGalley SOMETHING IS STIRRING IN THE HEART OF ILLINOIS When Jane and TJ agree to attend their high school reunion they never expect to come face-to-face with classmate-turned-stalker Lincoln the moment they return home. SOMETHING THAT SHOULD NEVER HAVE BEEN WOKEN Unspoken words fester between them of the incident in the local woods twenty years ago when Evie vanished in a flash of amber light. They were the last three people to see her alive. SOMETHING THAT SHOULD NEVER HAVE BEEN PROVOKED But the trees have been whispering to Lincoln ever since, and as Jane and TJ arrive back in town, the voices call to him again, hissing three solitary words: she is here. Sharp Objects meets Stranger Things in this razor-sharp small-town thriller - perfect for fans of Stephen King. What readers are saying: 'Will get under your skin and keep playing on your mind even after you finished reading. Really well written and fast-paced ... would definitely recommend, especially for a dark winter's evening!' Janaya, NetGalley 'Magnificent... a sci-fi thriller with spooky suspense that will be gobbled up by fans of the genre' Farshana, NetGalley 'The plot caught my imagination in a vice from the very beginning. This is a chilling, evocative psychological thriller that is totally addictive to the point I just can't stop thinking about it... An expertly written novel that is darkly compelling and razor-sharp' Robin, NetGalley 'Will have you on the edge of your seat the entire time!' Kori, NetGalley 'Full of twists and turns ... brilliantly written ... at times I just couldn't read quick enough to find out what was going to happen next' Rubie, NetGalley 'Wow this book is amazing - so many plot twists... I loved it!! I am really looking forward to reading more by this author' Gaynor, NetGalley 'Ideal for fans of genre-crossing psychological thrillers that include unexpected humour. Beautifully written' Rachel, NetGalley