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Photodynamic therapy (PDT) is increasingly being used amongst
health practitioners in combating a variety of diseases. One common
strategy used during this light activated process is to induce the
accumulation of significant amounts of a photosensitising agent in
the diseased tissue. The naturally occurring amino acid
5-aminovulinic acid (ALA) is used to produce high levels of the
photosensitizer, Protoprophyin IX, in the therapy known as ALA-PDT.
Written by experts in the field Photodynamic therapy with ALA
outlines a variety of clinical approaches to the topic, outlining
current applications. These include the use of ALA-PDT and ALA-FD
(fluorescence diagnosis) in the areas of dermatology, urology,
brain, otorhinolaryngology, gynaecology and gastroenterology. Also
included is a chapter that comprehensively reviews the scientific
principles of ALA-PDT. Primarily aimed at a clinical audience
Photodynamic therapy with ALA should provide a comprehensive review
and useful insight into ALA-PDT.
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