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Rapid Research Methods for Nurses, Midwives and Health
Professionals is designed to help you find and understand the
meaning of key research terminology and, more importantly, develop
your knowledge of some of the essential ideas and concepts they
describe. This A-Z dictionary of terms is a collection of over 200
entries with a definition of each word put in context with
additional tips on its use in assignment work. Alphabetically
arranged in an accessible, reader-friendly format, this book: *
Answers a clear demand for a practical, fast and concise
introduction to the key ideas, concepts and methods in nursing and
healthcare research * Provides students with fast and accessible
information designed for revision and writing research-based
assignments * Demystifies a field of study that students often find
daunting
This book describes the fascinating chemistry of the many kinds of
organic compounds of hypervalent iodine. Each chapter deals with a
particular iodine compound or families of compounds which have been
used as reagents in a plethora of useful transformations. These
include assorted oxidation, such as with the precious Dess-Martin
reagent as well as with a wide range of further reactions.
Prominent features of hypervalent iodine reagents derived from
iodobenzene are: ready availability, operational simplicity, mild
reaction conditions, and high efficiency. They are environmentally
safe and can be recycled. New species may be easily prepared by
introducing substituents in the benzene ring or changing the ligand
attached to iodine. Their combination with other reagents broadens
considerably their synthetic potential. Today, no synthetic chemist
can afford to ignore the valuable hypervalentiodine reagents.
Key Features
* Features up-to-date coverage of a wide range of topics
* Includes many tables featuring a diversity of reactivity, and a
comprehensive index
* Acts as a comprehensive, up-to-date reference on all aspects of
hypervalent iodine chemistry
* Contains a section on unusual efficiency of hypervalent iodine
reactions
Patients are beginning to benefit from antibody based, cellular and
vaccine approaches that are effective against genetically diverse
and therapy-resistance cancers. BCG immunotherapy is now being used
as a first line treatment for human bladder cancer and the
introduction of prophylactic vaccination against Hepatitis B and
HPV cancers is starting to show positive results. Following recent
FDA approval for a vaccination against prostate cancer, and
optimistic results in clinical trials for a vaccine targeting
cancer antigens in lung cancer, cancer immunotherapy is now
significantly impacting patient clinical management. Tumor
Immunology and Immunotherapy provides an up-to-date and
comprehensive account of cancer immunity and immunotherapy. It
discusses our adaptive and innate immunity to cancer, the
mechanisms underpinning our immune response, current approaches to
cancer immunotherapy, and how tumour and host responses can
circumvent effective anti-cancer immunity. The book examines recent
results, publications and current areas of interest including
'immune editing' and the specific issues that are affecting the
research and development of vaccines, providing insight into how
these problems may be overcome, as viewed by world leaders in the
field. Tumor Immunology and Immunotherapy will appeal to clinicians
working in oncology and cancer immunotherapy, and research
scientists including PhD and masters students, post-doctoral
researchers and senior investigators.
In 1965 a book by P. Bartlett appeared under the title "The
Nonclassical Ions" 1). The book is a collection of papers reprinted
from various journals. The many reviews that have appeared since
2-22) are either antiquated (the book published in 1972 12) covers
the literature mainly before 1968) or relatively biased (e.g.,
3.4,10" on brief 2, 7,11). This review attempts to discuss the
various points of view on the "nonclassical" carbocations. The main
point is to establish the relative role of "nonclassical" and
"classical" ions in various chemical processes. The author has
followed P. Bartlett's advice 1) that when setting forth the
achievements of the human mind one should see how we came to the
modern understanding of a given problem (" ... how we know what we
know"). The theory of "nonclassical" ions offers an explanation of
many unique chemical, stereochemical and kinetic peculiarities of
bicyclic compounds. It has expanded our knowledge on chemical bonds
in carbocations by introducing electron-deficient bonds (as in
boron hydrides). It has accounted for many rearrangements of stable
cations. As a "side" result our knowledge has been extended about
ionization processes in a solution, as well as about stereochemical
methods. 2 Main Terms of Nonclassical Carbocations In 1939 Hevell,
Salas and Wilson 23) assumed an intermediate, "bridge" ion 2 to be
formed when camphene hydrochloride 1 is rearranged into isobornyl
chloride 3. This happened 17 years after Meerwein first postulated
the intermediate formation of "carbonium" ions in chemical
reactions.
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