Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient.

Written for plant breeders, researchers and post-graduate students, this book provides a comprehensive review of the methods and underlying theoretical foundations used for selection in plant breeding programmes. The authors review basic elements of population and quantitative genetic theory, and consider in a unique way the tackling of the problems presented by soil heterogeneity and intergenotypic competition when selecting quantitative characters. The efficacy of different methods with regard to developing new varieties of crops are discussed for different modes of reproduction. This work provides a sound basis for informed decision making within the process of a selection programme.

This book provides a fresh, updated perspective of the current status and perspectives in genetic improvement of a diverse array of tropical crops. The first part covers aspects which are relevant across crops, namely how to maximize the use of genetic information through modern bioinformatic approaches and how to use statistics as a tool to sustain increased genetic gains and breeding efficiency. The second part of the book provides an updated view of some seed-propagated crops, such as rice, maize and oil palm, as well as crops propagated through vegetative means such as sweet potato, cassava, banana and sugarcane. Each chapter addresses the main breeding objectives, markets served, current breeding approaches, biotechnology, genetic progress observed, and in addition a glimpse into the future for each of these selected and important tropical crops.

The book presents a high-impact re-reading of core topics in the Marx and Marxist debates including: value-theory, the commodity-nature of money, complex or skilled labour, the determination of the value of labour-power and the nature of extraordinary surplus value. Drawing on this literature, the book provides original and innovative insights into key controversies in contemporary capitalism such as the increasingly intellectual character of commodity-producing labour, the emergence of global value chains, the relevance of ground-rent bearing commodities, and the specific, uneven developmental dynamics of "resource-rich" countries in the global process of capital accumulation. Contributing to the renewed vitality of critical studies of the economic works of Karl Marx, this book will be essential reading for all those interested in contemporary debates within Marxism, as well as readers of political economy, economics, development studies and economic sociology.

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient.

Oil palm is the world's most important oil crop and crossing is used extensively in the production of commercial seed, breeding and genetic studies. This book illustrates crossing techniques to maximise success and safeguard purity, enabling the production of high quality seeds to grow-on as planting material and in breeding superior cultivars. Presenting sound practices based on scientific innovation in plant breeding, this guide provides techniques integrated with expertise and application of sustainable aspects of agronomy and crop protection, alongside information and imaging technology. Promoting green, eco-friendly agriculture, this book covers: biology and genetics, germplasm, target traits and commercial crossing; health and safety considerations in the field and laboratory; pollen collection and storage, pollen viability testing, and pollination; isolation of the female inflorescence; and commercial tenera production. Based on experience and protocols, this is an invaluable manual for students and researchers in agriculture, plant breeders, growers and end users interested in the practicalities of oil palm crossing for breeding and commercial seed production

This is a hands-on, practical guide covering seedling screening for disease response in oil palm for pathology, breeding and genetics. Oil palm is the top oil crop in the world and Ganoderma is the most devastating disease of oil palm. The authors are all actively engaged in oil palm seed production and breeding and bring together the many aspects of seedling disease testing in to one integrated manual. Presenting sound practices based on scientific innovation and knowledge, this guide provides techniques integrated with expertise and also looks towards future possibilities. Promoting green, eco-friendly agriculture, this book covers: Health and safety considerations Media preparation for in vitro culture Collecting isolates and culture preparation Preparation of Ganoderma inoculum Nursery inoculation Scoring response Based on experience and protocols, this is an invaluable manual for students and researchers in agriculture, plant breeders, growers, traders and production companies interested in the practicalities of oil palm pathology. It provides a resource for training, a knowledge base for people new to oil palm and a reference guide for managers, to ensure best practices in maximising sustainability and production of this important crop.

This is a practical guide to mutation breeding in oil palm, representing completely novel work supported by the Plant Breeding and Genetics Section of the Joint FAO/IAEA Division (Vienna, Austria). Oil palm is the top oil crop and the only major crop and only oil crop not to have been improved by plant mutation breeding. The manual is hands-on, providing step-by-step illustrated methods in mutation induction, mutation detection and mutant line development for oil palm improvement. Presenting sound practices based on scientific innovation and knowledge, this guide provides techniques integrated with expertise and is authored by practitioners actively engaged in oil palm seed production and breeding. Promoting green, eco-friendly agriculture, this book features coverage of: Radio-sensitivity testing Challenges and opportunities for mutation breeding Protocol for developing mutant generations for mutant screening Services in irradiation treatments The only available resource containing protocols and guidelines on how oil palm can be manipulated for mutation breeding, this book is essential reading for oil palm breeders, seed producers and plantation companies, oil palm traders, students and research institutes across the world. It provides a resource for training, a knowledge base for people new to oil palm and a reference guide for managers, to ensure best practices in maximising sustainability and production of this important crop. .

This is a hands-on, practical guide to describe physical bunch and oil analysis of oil palm. Bunch and oil analysis laboratories are set up at oil mills to assess production, yield potential of plantations and oil extraction rates relative to targets. The higher the oil yields produced by the planting material, the less land that is needed to achieve a specific level of production, hence helping in the sustainability of the crop. Practical, illustrated steps are given in determining bunch and oil characteristics of oil palm. Promoting green, eco-friendly agriculture, this book covers: An introduction to bunch and oil analysis Health and safety considerations Bunch sampling Physical bunch analysis of stalks, spikelets, fruits and nuts Fruit sampling Nut analysis and measurements of components Oil analysis, oil extraction and measurement Calculation of bunch components and reporting. This is an invaluable manual for oil palm mill managers, oil palm plantation managers, palm oil producers, oil palm breeders, agronomists, oil chemists, oil palm seed producing companies and research institutes across the world (especially tropical zones). It is useful for those starting a career in oil palm production, as a reference guide for managers and for training purposes.

This is a hands-on practical guide to the use of Trichoderma as a biocontrol, as part of sustainable disease control measures for Ganoderma disease in oil palm plantations. The manual provides background information on Ganoderma (basal stem rot), the most devastating disease of oil palm in Southeast Asia, as well as on the benefits of Trichoderma fungi in safe guarding yields. The disease is caused by soil-borne fungi, Ganoderma spp, which are found in West Africa and South America, as well as Southeast Asia. Practical information is given on: the use of Trichoderma to manage Ganoderma for research and commercial use health and safety considerations in the laboratory, nursery and field in vitro multiplication of Trichoderma starting from media preparation and culture Ganoderma pathogenicity testing Trichoderma in vitro antagonism screening of Ganoderma Trichoderma screening to protect seedlings scoring Ganoderma response to Trichoderma in selecting aggressive Trichoderma isolates commercial use and application in oil palm plantations This is an invaluable manual for oil palm growers, estate/plantation managers, pathologists and breeders and research institutes across the world (especially tropical zones). It is also useful for those starting a career in oil palm plant protection, and as a reference guide for managers and for training purposes.

This is a hands-on, practical guide to general and specific practices in oil palm nurseries to produce healthy, vigorous and uniform plants ready for field planting. There are two nursery stages, pre-nursery and main nursery. The pre-nursery receives both germinated seeds and tissue culture produced plantlets (ramets) which are planted in a relatively small area in which shade and humidity can be controlled. Once young plants are established they are transferred to the main nursery, potted-on and grown on to produce field-ready plants. Good nursery practices, using sustainable approaches where possible, aim to provide high quality planting materials for both commercial production and field trialling. The book covers: Nursery set up - pre-nursery and main nursery Fertilizer programmes Watering Culling Weeding Pests and diseases Pre-field genotypic screening and selection Quarantine nurseries This is an invaluable manual for commercial seed producers, nursery plant producers, commercial plantation companies and plant breeders, as well as researchers in oil palm. It is useful for those starting a career in oil palm production, and as a reference guide for managers and for training purposes.

Written for plant breeders, researchers and post-graduate students, this excellent new book provides a comprehensive review of the methods and underlying theoretical foundations used for selection in plant breeding programs. The authors review basic elements of population and quantitative genetic theory, moving on to consider in a unique way the tackling of the problems presented by soil heterogeneity and intergenotypic competition when selecting quantitative characters.

THE UNDERGROUND NOVEL YOU WERE NEVER MEANT TO READ! "I'll commit suicide soon enough. Maybe before the end of this book, if we're both lucky. In fact, you can even think of what you're reading as the longest suicide note in history." Equal parts sex comedy, misanthropic rant, and hate letter to the world, THE MANIAC MANIFESTO is the radical confession of a self-proclaimed "ordinary man." By turns darkly humorous and outrageously offensive, it chronicles the exploits of its nameless anti-hero who, following an unhappy love affair, voluntarily descends into what he calls "the maggotlife"-a dark night of the soul from the depths of which issues the grim testament of a man determined to tell the absolute truth. Even if it kills him. Nihilistic, misogynistic, and apocalyptic, THE MANIAC MANIFESTO is a text like virtually no other-an admission of everything we've been taught to suppress, conceal, and never speak aloud, not to others, not even to ourselves.