Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it.

Longevity is used, sometimes, as synonymous with life-span and represents the ability of an organism to live longer than expected. However, the meaning of longevity goes beyond and includes a series of methods, tools and theories to extend healthier life. To achieve this goal, many scientists have turned their attention to a particular group of people, centenarians, who show signs of extreme longevity allowing them to live longer and most of the time healthier. Centenarians are the best example of extreme longevity in our species, they represent a selected population in which the appearance of major age-related diseases, such as cancer, cardiovascular and metabolic diseases among others, have been consistently delayed or escaped. In this book different aspect of longevity will be discussed and topics on immunology, molecular biology, genetics, diet and age-related diseases analyzed. Articles in this book were originally published as a thematic series in the journal Immunity & Ageing Volume 9, April 2012.