The series of volumes Progress in Surgical Pathology was conceived in an attempt to honor the 70th birthday of Dr. Raffaele Lattes. The original vol umes were the result of an initial call for papers dedicated to progress in the field of surgical pathology with contributors from all over the world. The pa pers published in these volumes have represented examples of classical clin ical pathologic correlations within the discipline of surgical pathology; other papers reflect the work being done at the interface between classical diagnos tic surgical pathology and research in the realm of immunology, molecular biology, cell biology, etc. These papers illustrate what is possible utilizing all of the advances made in basic biology, while remembering that the patholo gist remains an essential, crucial figure in the analysis of tissues, both with respect to their diagnosis as weil as the analysis of the dynamic interactions between cells. There have also been papers that may be characterized as philosophical or historical, which Iook at aspects of surgical pathology in a unique way. Five volumes have been published since 1980. The last of these was pub lished in 1983. For those of you who have been our loyal readers, you may wonder why there has been a gap in the publication of these volumes. This has been due to reorganization both among ourselves as weil as with the pub lisher."

****VERKAUFSKATEGORIE*** 0 e

Contents: The Use of Immunohistochemistry: Present and Future - The Expression of Vimentin in Epithelial Neoplasms - Morphologic Manifestations of Malignant Lymphomas in the Spleen. A Histologic and Immunohistochemical Study of 500 Biopsy Cases - Demonstration of Epstein-Barr Viral Genomes in Routine Paraffin Sections of Lymphoproliferative and Epithelial Lesions by in Situ Hybridization - Carcinoma of the Lung;Changing Sex Distribution and Histopathologic Cell Types - Pulmonary Pathology in Lung Transplant Patients - Bronchiolitis Obliterans with Organizing Pneumonia and Constrictive Bronchiolitis: Comparative Analysis ofTwo Distinct Entities - Lymphoid Interstitial Pneunomia in HIV Infected Individuals. Long-Term Clinicopathologic Observations in 52 Patients and Pathogenesis - Genital Human Papillomavirus (HPV) Infections and Their Associations with Squamous Cell Cancer: Reappraisal of the Morphologic, Epidemiologic and DNA Data - Central and Peripheral Bronchial Carcinoids Possess Distinct Peptide Immunostaining Patterns - Diagnosis of Rhabdomyosarcomas with Particular Reference to Immunohistochemical Markers - Borderline Lesionsof the Gastric Epithelium: New Indicators of Cancer Risk and Clinical Implications - The Pathology of Secondary Human Yolk Sac in Spontaneous Abortion: Findings in 103 Cases

This edition is devoted to benign gastrointestinal diseases and provides an in-depth discussion of many lesions, both common and uncommon. It is, for the most part, organised by category of disease rather than by anatomic site. This approach allows for comprehensive coverage of each entity and avoids redundant descriptions of lesions that occur in multiple regions of the gastrointestinal tract. Each disease entity is discussed from the point of view of its demographics, pathophysiology, clinical features, gross and microscopic pathology, and treatment. The text is heavily illustrated with diagrams and gross and microscopic photographs. Because of the extreme importance of clinical and endoscopic correlation with interpretation of gastrointestinal pathologic specimens, a practising gastroenterologist has been included among the authors. He has added endoscopic pictures and provides clinical insights critical to the understanding of gastrointestinal diseases. In many areas, the authors refer to animal models of disease since these have become powerful tools for understanding gastrointestinal diseases. They also discuss some of the molecular alterations that are present as these provide an understanding of the pathophysiology of the disease. Finally, the authors discuss the genetic predispositions to gastrointestinal diseases that occur as a result of genetic loss, mutation, overexpression of genes, or genetic polymorphisms.