To date, parasite diseases still affect millions of people world-wide, mainly in developing countries. The recent sequencing of parasite genomes opened a new era in parasitology research since the acquisition of new genomic data, providing a useful tool to analyse and compare gene structure, location and characteristics from different species to study evolution and gene function. This book is a collection of the recent findings of international experts in modern parasitology, computational biology, evolutionary biology, and genetics. It includes specific data on the current knowledge and understanding of genome organisation, dynamic and function for Plasmodium falciparum, Trypanosoma spp., Leishmania spp., Trichomonas vaginalis, Giardia lamblia, Entamoeba histolytica and Microsporidium, which represent the main causes of parasitic infections in humans. This book will be an essential reference for all parasitologists and scientists, as well as researchers, postdoctoral fellows and graduate students in computational biology, evolutionary biology, and genetics.

MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and therapeutic targets. In addition it discusses the potential use in translational medicine. Chapters in this book present comprehensive and expert perspectives on the roles of miRNAs in most common cancers from bench to bedside applications and are written by an international team of renowned experts in the field. This book is a landmark work providing up-to-date research on miRNAs and their important roles in cancer translational research.