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In order to understand common conditions such as coeliac disease
and Crohn's disease, one must view the gut in its evolutionary
context. This is the novel approach to the gut and its diseases
that is adopted in this book. The first part tells the story of the
evolution of the gut itself - why it came about and how it has
influenced the evolution of animals ever since. The second part
focuses on the evolution of immunity and how the layers of immune
mechanisms are retained in the gut, resembling the strata revealed
in an archeological dig. The final part, 'The Gastro-Archeologist',
ties the first two together and highlights how understanding the
gut and immune system in their evolutionary context can help us
understand diseases affecting them. Ambitious in its scope but
telling a unique story from a refreshingly novel perspective, the
book offers an informative and enjoyable read. As the story of the
gut, immunity and disease unfolds, the author aims to endow readers
with the same sense of awe and excitement that the subject evokes
in him. Difficult concepts are illustrated using simple and
colourful analogies, and the main content is supplemented with
anecdotes and unusual and amusing facts throughout the book. The
book is intended for anyone with an interest in the gut, its
immunity and diseases, ranging from school and college biology and
biomedical students, to professionals working in the field, and to
patients suffering from intestinal diseases who want to understand
more about their conditions.
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