Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology. Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice. In the Molecular Pathology Library series the basic science and the technology is integrated with the medical perspective and clinical application. Each book in the series is divided according to neoplastic and non-neoplastic diseases for each of the organ systems traditionally associated with medical subspecialties.

Each book in the series is organized to provide (1) a succinct background of the essential terminology, concepts and technology of molecular biology, (2) an overview of the broad application of molecular biology principles to disease and (3) specific application of molecular pathology to the pathogenesis, diagnosis and treatment of neoplastic and non-neoplastic diseases specific to each organ system. These broad section topics will be broken down into succinct chapters, averaging about 15 to 20 pages each, to cover a very specific disease entity. The chapters will be written by established authorities on the specific topic from academic centers around the world. In one book, diverse subjects are included that the reader would have to pursue from multiple sources in order to have a clear understanding of the molecular pathogenesis, diagnosis and treatment of specific diseases. Attempting to hunt for the full information from basic concept to specific applications for a disease from the varied sources is time-consuming and frustrating. By providing this quick and user-friendly reference, understanding and application of this rapidly growing field is made more accessible to both expert and generalist alike.

As books that bridge the gap between basic science and clinical understanding and practice, the Molecular Pathology Series serves the basic scientist, the clinical researcher and the practicing physician or other health care provider who require more understanding of the application of basic research to patient care, from "bench to bedside." This series is unique and an invaluable resource. These books will be indispensable to physicians and health care providers in multiple disciplines as noted above, to residents and fellows in these multiple disciplines as well as their teaching institutions and to researchers who increasingly must justify the clinical implications of their research.

The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Lymph Nodes highlights the usefulness of techniques such as touch preparation cytology and fine needle aspiration (FNA) cytology, as well as FNA biopsy. This fascicle also suggests proper handling for subsequent ancillary studies, including flow cytometric, cytogenetic, and molecular studies. Special emphasis is given to the limitations of frozen section diagnosis in lymph node pathology. All chapters are written by experts in their fields and include the most up to date scientific information. This book serves as a very useful resource for physicians in the frozen section room and in intra-operative consultation situations dealing with, and interested in, this very complex field of diagnostic pathology. Frozen Section Library: Lymph Nodes is of great value to pathologists, residents, and fellows who diagnose pathologic processes involving lymph nodes. Cherie H. Dunphy, M.D. is Professor of Pathology and Laboratory Medicine, Executive Director of Hematopathology and Hematopathology Fellowship Department of Pathology and Laboratory Medicine University of North Carolina Chapel Hill, NC.

Unlike similar texts, which are often laden in technological details, Cherie Dunphy offers a comprehensive flow cytometry textbook, which covers in great depth, the technical aspects of FCI, phenotypic markers, as well as the advantages and disadvantages of FCI, but also a quick diagnostic guide incorporating normal and abnormal phenotypic findings of peripheral blood, body fluids, bone marrow, and lymph nodes. Integration of flow cytometry immunophenotyping with morphology and molecular genetic findings provides a complete diagnostic picture. The diagnostic applications of FCI in combination with morphology for all important hematolymphoid disorders. Detailed discussions of FCI mirror the new 2008 WHO classification, to increase the ease of use for practicing hematopathologists and residents. Separate chapters detail unique applications of FCI. Brand new: 2008 WHO Classification