This book presents the mathematics behind the formulation, approximation, and numerical analysis of contact and friction problems. It also provides a survey of recent developments in the numerical approximation of such problems as well as several remaining unsolved issues. Particular focus is placed on the Signorini problem and on frictionless unilateral contact in small strain. The final chapters cover more complex, applications-oriented problems, such as frictional contact, multi-body contact, and large strain. Finite Element Approximation of Contact and Friction in Elasticity will be a valuable resource for researchers in the area. It may also be of interest to those studying scientific computing and computational mechanics.

Following the succesful publication of "Proteome and Protein Analysis" in 2000, which was based on a former MPSA (Methods in Protein Structure Analysis) conference, Methods in Proteome and Protein Analysis presents the most interesting papers from the 14th MPSA meeting.

Major topics include: protein and peptide sample preparation and separation; new reagent for protein sequence analysis; mass spectrometry in protein research; analysis of posttranslational modification; protein-protein interaction using MALDI-MS; manipulation of genome or functional compositon trap; structure-function correlation study using optical biosensors of microcolorimetrical techniques; structural proteomics as NMR or fluorescence polarization study; the classification and prediction of structure or functional sites; in silico analysis of proteins and proteomes; increasing throughput and data quality for proteomics.

This title features 15 original craft projects inspired by the Minecraft video game sensation. Creepers, characters, tools and blocks are fun to create now and play with later. It is suitable for children aged eight and over. Bring your Minecraft adventure to life with easy-to-make craft projects! Use this imaginative book to create instantly recognisable toys, jewellery, wearables, and accessories, based on one of the most popular video games of all time. Author Choly Knight shows you how to quickly make real life versions of all your favourite Minecraft characters and game elements, using only a few basic craft supplies. The blocky pixilated graphics of Minecraft are perfect for so many different kinds of crafts. Inside you'll find 15 fun step-by-step projects for perler beads, duct tape, paper crafting, painting, sewing, and crocheting. So get in "creative mode" and celebrate the limitless possibilities of Minecraft!

Pillows are one of the easiest items to sew, and one of the most affordable ways to add a splash of color and personality to a room. With twelve cute and cuddly animal pillows to make, and easy-to-follow, step-by-step instructions, seamstresses of all skill levels will enjoy making them. It is so easy to create these adorable pet pillows - all that's needed is a sewing machine, some inexpensive fabric, and a few basic sewing tools. The hardest part will be deciding which pillow to make first!

Pixel Craft with Perler Beads is a fun project book containing more than 50 exciting design ideas for digital-inspired jewellery, coasters, frames, boxes, toys and more, using fusible craft beads. With no crafting experience necessary, you'll produce great results in no time thanks to Choly Knight's clear directions and step-by-photographs!Colourful, inexpensive beads from Perler(R), Hama(R), or Artkal(R) are ideal for recreating the retro 8-bit era of blocky video games. As well as learning the basics of assembling and fusing beads, you'll also pick up useful tips on tools, pegboards and adhesives.Making trendy pixelated wearables, jewellery and decorations for your home has never been easier or more enjoyable. Your creations will look as if they have just stepped off a screen!

This is the perfect book for beginner sewers, with friendly and easy-to-follow directions. Sew Me! Sewing Basics is geared towards would-be sewers of all ages, who may never have touched a sewing machine or even threaded a needle before. It's the perfect book for anyone who wants to get started in the craft, or just needs a quick refresher course in sewing. Choly Knight's friendly and easy-to-follow directions will get readers sewing with confidence, making repairs and creating new garments from scratch. She starts at the very beginning, showing how to choose a sewing machine and introducing the most basic techniques and shortcuts. From cutting patterns and sewing seams, to binding edges, gathering fabric and installing zippers, each new skill is accompanied by a quick practice exercise to try, allowing readers to learn as they sew. 36 simple and straightforward projects are provided for sewing fun accessories from plushies, pincushions and placemats to hand towels and hats.

"Protein Structure Analysis - Preparation and Characterization" is a compilation of practical approaches to the structural analysis of proteins and peptides. Here, about 20 authors describe and comment on techniques for sensitive protein purification and analysis. These methods are used worldwide in biochemical and biotechnical research currently being carried out in pharmaceu tical and biomedical laboratories or protein sequencing facilities. The chapters have been written by scientists with extensive ex perience in these fields, and the practical parts are well documen ted so that the reader should be able to easily reproduce the described techniques. The methods compiled in this book were demonstrated in student courses and in the EMBO Practical Course on "Microsequence Analysis of Proteins" held in Berlin September 10-15, 1995. The topics also derived from a FEBS Workshop, held in Halkidiki, Thessaloniki, Greece, in April, 1995. Most of the authors participated in these courses as lecturers and tutors and made these courses extremely lively and successful. Since polypeptides greatly vary depending on their specific structure and function, strategies for their structural analysis must for the most part be adapted to each individual protein. Therefore, advantages and limitations of the experimen tal approaches are discussed here critically, so that the reader becomes familiar with problems that might be encountered."

The papers selected here cover new, sensitive and rapid methods for the analysis of proteins, with special emphasis on the proteome. In addition to the experimental details, the advantages and limitations of the methodological approaches are discussed, and topics include sequencing analysis, sample preparation, mass spectrometry, NMR, analysis of post-translational modifications, purification of recombinant proteins, protein-protein and protein-DNA interactions, structure prediction, modeling and folding, functional implications of domains and newly emerging investigative methods, allowing analysis of the expression of genes.