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This book is formulated from the papers presented at the
International Symposium on "Membrane Biochemistry and
Bioenergetics," held at the Rensselaerville Institute,
Rensselaerville, New York, August 1986, in honor of Tsoo E. King on
the occasion of the 30th anniversary of reconstitution of
arespiratory chain system by Professor David Keilin and Tsoo E.
King. Professor Tsoo E. King, to whom this volume is dedicated, has
made enormous contributions to the field of isolation and
reconstitution of membrane proteins and has continued to explore
the frontiers of bioener getics. In particular, his persistent
proposals on the existence of ubiquinone binding proteins from
conceptualization to experimentation eventually convinced many
scientists to study these proteins further . Professor King's
preparation of reconstitutively active succinate dehydrogenase
opened a new avenue in the fie1d of membrane bioenergetics, and his
work has been greatly appreciated. The purpose of the symposium was
to bring together scientists from diverse disciplines related to
membrane bioenergetics to discuss the recent developments in the
field. This symposium, initiated by the Capital District
Bioenergetics Group, was attended by 100 scientists, 80 of whom
presented their recent discoveries. The symposium was arranged in a
sequence of platform lectures, poster presentations and discussion
sessions so that all the participants had opportunities to discuss
the subjects presented. Most of the participants contributed a
chapter to this volume. We would like to express our regret to many
other scientists including Professor King's friends, colleagues and
students who could not attend due to various reasons."
The emergence of the Biochemical Sciences is underlined by the FAOB
symposium in Seoul and highlighted by this Satellite meeting on the
"New Bioenergetics. " Classical mitochondrial electron transfer and
energy coupling is now complemented by the emerging molecular
biology of the respiratory chain which is studied hand in hand with
the recognition of mitochondrial disease as a major and emerging
study in the basic and clinical medical sciences. Thus, this
symposium has achieved an important balance of the fundamental and
applied aspects of bioenergetics in the modern setting of molecular
biology and mitochondrial disease. At the same time, the symposium
takes note not only of the emerging excellence of Biochemical
Studies in the Orient and indeed in Korea itself, but also
retrospectively enjoys the history of electron transport and energy
conservation as represented by the triumvirate ofYagi, King and
Slater. Many thanks are due Drs. Kim and Ozawa for their elegant
organization of this meeting and its juxtaposition to the FAOB
Congress. Britton Chance April 2, 1990 v PREFACE This book contains
the contributed papers presented at the "International Symposium on
Bioenergetics: Molecular Biology, Biochemistry and Pathology," held
in Seoul, Korea, August 18-21, 1989, sponsored by International
Union of Biochemistry (as ruB Symposium No. 191) and Ewha Womans
University, Seoul, Korea. The symposium was held in honor of
Professor Kunio Yagi to commemorate his 70th birthday.
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