Christian Kohler covers the connection between uC and simulation, the interface abstraction as well as the analysis and optimization of coupling systems with the Chip-Hardware-in-the-Loop Simulation (CHILS) approach. He develops the hardware to simulation coupling system with a focus on less hardware effort, the capabilities to couple with different simulation environments, and the efficiency of coupling. Furthermore, the author presents existing concepts to simulate complex systems and compares them with the new approach.