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This book is driven by the considerable progress made by novel
imaging techniques in understanding the pathophysiology and
evolution of aortic disease and its diagnosis. Despite the lack of
symptoms in stable conditions, most aortic diseases have a high
morbidity and mortality. New therapeutic strategies such as
endovascular treatment and surgical techniques have appeared to
improve conventional surgery in advanced phases of the disease, but
until recently, medical treatment has focused on the control of
cardiovascular risk factors using beta-blockers to reduce aortic
wall stress by reducing blood pressure and heart rate.
Pharmacotherapy in Aortic Disease updates the reader on the new
medical treatment that are changing the natural history of these
diseases. Leading experts have created a critical in-depth, yet
concise, analysis of the available medical treatments for different
aortic disease entities. Both basic research studies and clinical
trials discussed in this book serve as a base for improving
therapeutic management, delaying the need for surgery, and
prolonging survival in these patients.
Aortic dissection affects approximately two in ten thousand
individuals and can be fatal. This state-of the-art publication is
a result of the combined efforts of participants from the
International Registry of Aortic Dissection (IRAD). The book has
been divided into sections. Each chapter provides a succinct
overview of the current clinical literature and incorporates
illustrations for further explanation.
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